Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
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| Title: | Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells. |
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| Authors: | Fortin J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Chiang MF; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Meydan C; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Al-Saud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065.; WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY 10065., Foox J; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Al-Saud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065., Ramachandran P; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Leca J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Lemonnier F; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.; Institut Mondor de Recherche Biomédicale, INSERMU955, Université Paris Est Créteil, Créteil 94010, France., Li WY; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China., Gams MS; Department of Immunology, The Hospital for Sick Children Research Institute, University of Toronto, Toronto, ON M5G 0A4, Canada., Sakamoto T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.; Department of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan., Chu M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Tobin C; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Laugesen E; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Robinson TM; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.; Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065., You-Ten A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Butler DJ; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065., Berger T; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada., Levine RL; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065.; Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY 10065.; Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY 10065., Guidos CJ; Department of Immunology, The Hospital for Sick Children Research Institute, University of Toronto, Toronto, ON M5G 0A4, Canada., Melnick AM; Department of Medicine, Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, NY 10021., Mason CE; Department of Physiology and Biophysics, Weill Cornell Medicine, New York, NY 10065.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Al-Saud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY 10065.; WorldQuant Initiative for Quantitative Prediction, Weill Cornell Medicine, New York, NY 10065., Mak TW; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2C1, Canada.; Centre for Oncology and Immunology, Hong Kong Science Park, Hong Kong SAR, China.; Department of Pathology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China. |
| Source: | Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Jan 24; Vol. 120 (4), pp. e2208176120. Date of Electronic Publication: 2023 Jan 18. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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