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A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.

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Title: A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
Authors: Li L; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Wen Y; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Wrapp D; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA., Jeong J; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Zhao P; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Xiong W; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Atkins CL; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Shan Z; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650106, China., Hui D; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA., Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Ju C; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Source: Antibody therapeutics [Antib Ther] 2022 Nov 07; Vol. 6 (1), pp. 1-12. Date of Electronic Publication: 2022 Nov 07 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 101730822 Publication Model: eCollection Cited Medium: Internet ISSN: 2516-4236 (Electronic) Linking ISSN: 25164236 NLM ISO Abbreviation: Antib Ther Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel humanized Chi3l1 blocking antibody attenuates acetaminophen-induced liver injury in mice.
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  Data: <searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wen+Y%22">Wen Y</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Wrapp+D%22">Wrapp D</searchLink>; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22Jeong+J%22">Jeong J</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+P%22">Zhao P</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Xiong+W%22">Xiong W</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Atkins+CL%22">Atkins CL</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Shan+Z%22">Shan Z</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.; Center for Life Sciences, School of Life Sciences, Yunnan University, Kunming 650106, China.<br /><searchLink fieldCode="AU" term="%22Hui+D%22">Hui D</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22McLellan+JS%22">McLellan JS</searchLink>; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Ju+C%22">Ju C</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22An+Z%22">An Z</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
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