Nonskeletal and skeletal effects of high doses versus low doses of vitamin D3 in renal transplant recipients: Results of the VITALE (VITamin D supplementation in renAL transplant recipients) study, a randomized clinical trial.

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Title: Nonskeletal and skeletal effects of high doses versus low doses of vitamin D3 in renal transplant recipients: Results of the VITALE (VITamin D supplementation in renAL transplant recipients) study, a randomized clinical trial.
Authors: Courbebaisse M; Paris University; Physiology Department, European Georges-Pompidou Hospital, APHP; INSERM U1151. Paris, France. Electronic address: marie.courbebaisse@aphp.fr., Bourmaud A; APHP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC 1426, F-75019 Paris, France; Université de Paris, ECEVE UMR 1123, INSERM. F-75010 Paris, France., Souberbielle JC; Service des explorations fonctionnelles hôpital Necker-Enfants Malades, DMU Biophygen, GHU Centre Université de Paris APHP. Paris, France., Sberro-Soussan R; Université de Paris; Service de Transplantation Rénale et Néphrologie, Hôpital Necker Enfant Malades, APHP. Paris, France., Moal V; Aix-Marseille Université - AP-HM - Hôpital Conception - Centre de Néphrologie et Transplantation Rénale. Marseille, France., Le Meur Y; Department of Nephrology, CHU de Brest; UMR1227, Lymphocytes B et Autoimmunité, Université de Brest, Inserm, Labex IGO. Brest, France., Kamar N; Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, INSERM U1043, IFR -BMT, University Paul Sabatier. Toulouse, France., Albano L; Service de Transplantation Rénale, CHU de Nice. Nice, France., Thierry A; Service de Néphrologie, INSERM U1082 et Fédération Hospitalo-Universitaire BIOSUPORT. Poitiers, France., Dantal J; CRTI (Centre de Recherche en Transplantation et Immunologie) INSERM UMR1064, Université de Nantes, Centre Hospitalier Universitaire de Nantes. Nantes, France., Danthu C; Department of Nephrology, Limoges University hospital; UMR INSERM 1092, RESINFIT, Limoges University hospital 2. Limoges, France., Moreau K; Unité de transplantation rénale, Hôpital Pellegrin, CHU de Bordeaux. Bordeaux, France., Morelon E; Service de transplantation, néphrologie et immunologie clinique, Hôpital Edouard Herriot, Hospices Civils de Lyon; INSERM U1111, Université Claude Bernard Lyon1. Lyon, France., Heng AE; Service de Néphrologie, Dialyse, Transplantation, CHU de Clermont-Ferrand; Université Clermont Auvergne. F-63000 Clermont-Ferrand, France., Bertrand D; Nephrology, dialysis and kidney transplantation, Rouen University Hospital. Rouen, France., Arzouk N; Service de Transplantation Rénale, hôpital La Pitié-Salpétrière, APHP. Paris, France., Perrin P; Department of Nephrology and Transplantation, Strasbourg University Hospital; Fédération de Médecine Translationnelle, INSERM U1109, LabEx TRANSPLANTEX. Strasbourg, France., Morin MP; CHU Pontchaillou, service de Néphrologie. Rennes, France., Rieu P; Division of Nephrology, Reims university hospital, CRNS UMR 7369 MEDyC laboratory. Reims, France., Presne C; Nephrology Internal Medicine Dialysis Transplantation Department, Amiens University Hospital. Amiens France., Grimbert P; Nephrology and Transplant Department, CHU Henri-Mondor, APHP; Université Paris Est Créteil, INSERM U955. Paris, France., Ducloux D; Department of Nephrology, CHU Besançon. Besançon, France., Büchler M; Department of Nephrology and Transplantation, CHU Tours; University of Tours, EA4245 Transplantation, Immunology, Inflammation; FHU SUPORT. Tours, France., Le Quintrec M; Hôpital Foch, Nephrology department. Suresnes, France., Ouali N; Nephrology department, SINRA, Hôpital Tenon. Paris, France., Pernin V; University of Montpellier, Department of Nephrology, Dialysis and Transplantation, Montpellier University hospital; Institute for Regenerative Medicine & Biotherapy (IRMB), INSERM U1183. Montpellier, France., Bouvier N; Service de Néphrologie-Dialyse-Transplantation, CHU Caen Normandie; Université de Caen Normandie. Caen, France., Durrbach A; Université Paris Saclay, France; INSERM UMR 1186, Gustave Roussy. Villejuif, France; Nephrology Department, Bicêtre Hospital APHP. Le Kremlin-Bicêtre, France., Alamartine E; CHU de Saint Etienne et CIRI - INSERM U1111 - CNRS UMR5308 - ENS Lyon/UCBL1/Université St Etienne. Saint Etienne, France., Randoux C; Service de Néphrologie, CHU Bichat Claude Bernard, APHP.Nord. Paris, France., Besson V; Service de Néphrologie-Dialyse-transplantation, CHU d'Angers. Angers, France., Hazzan M; Université de Lille, INSERM, CHU Lille, U1286 - Infinite - Institute for Translational Research in Inflammation. F-59000 Lille, France., Pages J; APHP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d'Epidémiologie Clinique, INSERM, CIC 1426. F-75019 Paris, France., Colas S; Unité de Recherche Clinique Necker-Cochin, APHP. Paris, France., Piketty ML; Service des explorations fonctionnelles hôpital Necker-Enfants Malades, DMU Biophygen, GHU Centre Université de Paris APHP. Paris, France., Friedlander G; Fondation Université de Paris. Paris, France., Prié D; Université de Paris; INSERM U1151, service des explorations fonctionnelles hôpital Necker-Enfants Malades, DMU Biophygen, GHU Centre Université de Paris APHP. Paris, France., Alberti C; APHP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC 1426, F-75019 Paris, France; Université de Paris, ECEVE UMR 1123, INSERM. F-75010 Paris, France., Thervet E; Paris University; Nephrology Department, European Georges-Pompidou Hospital, APHP; INSERM UMR 970, Paris Cardiovascular Research Center. Paris, France.
Source: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2023 Mar; Vol. 23 (3), pp. 366-376. Date of Electronic Publication: 2023 Jan 09.
Publication Type: Randomized Controlled Trial; Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 100968638 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-6143 (Electronic) Linking ISSN: 16006135 NLM ISO Abbreviation: Am J Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Nonskeletal and skeletal effects of high doses versus low doses of vitamin D<subscript>3</subscript> in renal transplant recipients: Results of the VITALE (VITamin D supplementation in renAL transplant recipients) study, a randomized clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Courbebaisse+M%22">Courbebaisse M</searchLink>; Paris University; Physiology Department, European Georges-Pompidou Hospital, APHP; INSERM U1151. Paris, France. Electronic address: marie.courbebaisse@aphp.fr.<br /><searchLink fieldCode="AU" term="%22Bourmaud+A%22">Bourmaud A</searchLink>; APHP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC 1426, F-75019 Paris, France; Université de Paris, ECEVE UMR 1123, INSERM. F-75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Souberbielle+JC%22">Souberbielle JC</searchLink>; Service des explorations fonctionnelles hôpital Necker-Enfants Malades, DMU Biophygen, GHU Centre Université de Paris APHP. Paris, France.<br /><searchLink fieldCode="AU" term="%22Sberro-Soussan+R%22">Sberro-Soussan R</searchLink>; Université de Paris; Service de Transplantation Rénale et Néphrologie, Hôpital Necker Enfant Malades, APHP. Paris, France.<br /><searchLink fieldCode="AU" term="%22Moal+V%22">Moal V</searchLink>; Aix-Marseille Université - AP-HM - Hôpital Conception - Centre de Néphrologie et Transplantation Rénale. Marseille, France.<br /><searchLink fieldCode="AU" term="%22Le+Meur+Y%22">Le Meur Y</searchLink>; Department of Nephrology, CHU de Brest; UMR1227, Lymphocytes B et Autoimmunité, Université de Brest, Inserm, Labex IGO. Brest, France.<br /><searchLink fieldCode="AU" term="%22Kamar+N%22">Kamar N</searchLink>; Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, INSERM U1043, IFR -BMT, University Paul Sabatier. Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Albano+L%22">Albano L</searchLink>; Service de Transplantation Rénale, CHU de Nice. Nice, France.<br /><searchLink fieldCode="AU" term="%22Thierry+A%22">Thierry A</searchLink>; Service de Néphrologie, INSERM U1082 et Fédération Hospitalo-Universitaire BIOSUPORT. Poitiers, France.<br /><searchLink fieldCode="AU" term="%22Dantal+J%22">Dantal J</searchLink>; CRTI (Centre de Recherche en Transplantation et Immunologie) INSERM UMR1064, Université de Nantes, Centre Hospitalier Universitaire de Nantes. Nantes, France.<br /><searchLink fieldCode="AU" term="%22Danthu+C%22">Danthu C</searchLink>; Department of Nephrology, Limoges University hospital; UMR INSERM 1092, RESINFIT, Limoges University hospital 2. Limoges, France.<br /><searchLink fieldCode="AU" term="%22Moreau+K%22">Moreau K</searchLink>; Unité de transplantation rénale, Hôpital Pellegrin, CHU de Bordeaux. Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Morelon+E%22">Morelon E</searchLink>; Service de transplantation, néphrologie et immunologie clinique, Hôpital Edouard Herriot, Hospices Civils de Lyon; INSERM U1111, Université Claude Bernard Lyon1. Lyon, France.<br /><searchLink fieldCode="AU" term="%22Heng+AE%22">Heng AE</searchLink>; Service de Néphrologie, Dialyse, Transplantation, CHU de Clermont-Ferrand; Université Clermont Auvergne. F-63000 Clermont-Ferrand, France.<br /><searchLink fieldCode="AU" term="%22Bertrand+D%22">Bertrand D</searchLink>; Nephrology, dialysis and kidney transplantation, Rouen University Hospital. Rouen, France.<br /><searchLink fieldCode="AU" term="%22Arzouk+N%22">Arzouk N</searchLink>; Service de Transplantation Rénale, hôpital La Pitié-Salpétrière, APHP. Paris, France.<br /><searchLink fieldCode="AU" term="%22Perrin+P%22">Perrin P</searchLink>; Department of Nephrology and Transplantation, Strasbourg University Hospital; Fédération de Médecine Translationnelle, INSERM U1109, LabEx TRANSPLANTEX. Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Morin+MP%22">Morin MP</searchLink>; CHU Pontchaillou, service de Néphrologie. Rennes, France.<br /><searchLink fieldCode="AU" term="%22Rieu+P%22">Rieu P</searchLink>; Division of Nephrology, Reims university hospital, CRNS UMR 7369 MEDyC laboratory. Reims, France.<br /><searchLink fieldCode="AU" term="%22Presne+C%22">Presne C</searchLink>; Nephrology Internal Medicine Dialysis Transplantation Department, Amiens University Hospital. Amiens France.<br /><searchLink fieldCode="AU" term="%22Grimbert+P%22">Grimbert P</searchLink>; Nephrology and Transplant Department, CHU Henri-Mondor, APHP; Université Paris Est Créteil, INSERM U955. Paris, France.<br /><searchLink fieldCode="AU" term="%22Ducloux+D%22">Ducloux D</searchLink>; Department of Nephrology, CHU Besançon. Besançon, France.<br /><searchLink fieldCode="AU" term="%22Büchler+M%22">Büchler M</searchLink>; Department of Nephrology and Transplantation, CHU Tours; University of Tours, EA4245 Transplantation, Immunology, Inflammation; FHU SUPORT. Tours, France.<br /><searchLink fieldCode="AU" term="%22Le+Quintrec+M%22">Le Quintrec M</searchLink>; Hôpital Foch, Nephrology department. Suresnes, France.<br /><searchLink fieldCode="AU" term="%22Ouali+N%22">Ouali N</searchLink>; Nephrology department, SINRA, Hôpital Tenon. Paris, France.<br /><searchLink fieldCode="AU" term="%22Pernin+V%22">Pernin V</searchLink>; University of Montpellier, Department of Nephrology, Dialysis and Transplantation, Montpellier University hospital; Institute for Regenerative Medicine & Biotherapy (IRMB), INSERM U1183. Montpellier, France.<br /><searchLink fieldCode="AU" term="%22Bouvier+N%22">Bouvier N</searchLink>; Service de Néphrologie-Dialyse-Transplantation, CHU Caen Normandie; Université de Caen Normandie. Caen, France.<br /><searchLink fieldCode="AU" term="%22Durrbach+A%22">Durrbach A</searchLink>; Université Paris Saclay, France; INSERM UMR 1186, Gustave Roussy. Villejuif, France; Nephrology Department, Bicêtre Hospital APHP. Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Alamartine+E%22">Alamartine E</searchLink>; CHU de Saint Etienne et CIRI - INSERM U1111 - CNRS UMR5308 - ENS Lyon/UCBL1/Université St Etienne. Saint Etienne, France.<br /><searchLink fieldCode="AU" term="%22Randoux+C%22">Randoux C</searchLink>; Service de Néphrologie, CHU Bichat Claude Bernard, APHP.Nord. Paris, France.<br /><searchLink fieldCode="AU" term="%22Besson+V%22">Besson V</searchLink>; Service de Néphrologie-Dialyse-transplantation, CHU d'Angers. Angers, France.<br /><searchLink fieldCode="AU" term="%22Hazzan+M%22">Hazzan M</searchLink>; Université de Lille, INSERM, CHU Lille, U1286 - Infinite - Institute for Translational Research in Inflammation. F-59000 Lille, France.<br /><searchLink fieldCode="AU" term="%22Pages+J%22">Pages J</searchLink>; APHP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d'Epidémiologie Clinique, INSERM, CIC 1426. F-75019 Paris, France.<br /><searchLink fieldCode="AU" term="%22Colas+S%22">Colas S</searchLink>; Unité de Recherche Clinique Necker-Cochin, APHP. Paris, France.<br /><searchLink fieldCode="AU" term="%22Piketty+ML%22">Piketty ML</searchLink>; Service des explorations fonctionnelles hôpital Necker-Enfants Malades, DMU Biophygen, GHU Centre Université de Paris APHP. Paris, France.<br /><searchLink fieldCode="AU" term="%22Friedlander+G%22">Friedlander G</searchLink>; Fondation Université de Paris. Paris, France.<br /><searchLink fieldCode="AU" term="%22Prié+D%22">Prié D</searchLink>; Université de Paris; INSERM U1151, service des explorations fonctionnelles hôpital Necker-Enfants Malades, DMU Biophygen, GHU Centre Université de Paris APHP. Paris, France.<br /><searchLink fieldCode="AU" term="%22Alberti+C%22">Alberti C</searchLink>; APHP.Nord-Université de Paris, Hôpital Universitaire Robert Debré, Unité d'Epidémiologie Clinique, Inserm, CIC 1426, F-75019 Paris, France; Université de Paris, ECEVE UMR 1123, INSERM. F-75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Thervet+E%22">Thervet E</searchLink>; Paris University; Nephrology Department, European Georges-Pompidou Hospital, APHP; INSERM UMR 970, Paris Cardiovascular Research Center. Paris, France.
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