Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.

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Title: Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.
Authors: May S; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Müller M; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Livingstone CR; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Skalka GL; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Walsh PJ; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Hedley A; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Shaw R; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Clark W; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Vande Voorde J; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Officer-Jones L; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Ballantyne F; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Powley IR; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Drake TM; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK., Kiourtis C; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Keith A; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Rocha AS; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Tardito S; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; Department of Histopathology, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, UK., Bushell M; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Bird TG; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, EH164TJ, UK. Electronic address: t.bird@beatson.gla.ac.uk.
Source: Journal of hepatology [J Hepatol] 2023 May; Vol. 78 (5), pp. 1028-1036. Date of Electronic Publication: 2023 Jan 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1600-0641
DOI:10.1016/j.jhep.2023.01.009