Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.

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Title: Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.
Authors: May S; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Müller M; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Livingstone CR; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Skalka GL; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Walsh PJ; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Nixon C; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Hedley A; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Shaw R; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Clark W; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Vande Voorde J; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Officer-Jones L; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Ballantyne F; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Powley IR; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Drake TM; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK., Kiourtis C; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Keith A; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Rocha AS; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Tardito S; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Sumpton D; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK., Le Quesne J; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; Department of Histopathology, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, UK., Bushell M; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Sansom OJ; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK., Bird TG; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, EH164TJ, UK. Electronic address: t.bird@beatson.gla.ac.uk.
Source: Journal of hepatology [J Hepatol] 2023 May; Vol. 78 (5), pp. 1028-1036. Date of Electronic Publication: 2023 Jan 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration.
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  Data: <searchLink fieldCode="AU" term="%22May+S%22">May S</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Müller+M%22">Müller M</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Livingstone+CR%22">Livingstone CR</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Skalka+GL%22">Skalka GL</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Walsh+PJ%22">Walsh PJ</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Nixon+C%22">Nixon C</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Hedley+A%22">Hedley A</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Shaw+R%22">Shaw R</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Clark+W%22">Clark W</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Vande+Voorde+J%22">Vande Voorde J</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Officer-Jones+L%22">Officer-Jones L</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Ballantyne+F%22">Ballantyne F</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Powley+IR%22">Powley IR</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Drake+TM%22">Drake TM</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; Centre for Medical Informatics, Usher Institute, University of Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22Kiourtis+C%22">Kiourtis C</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Keith+A%22">Keith A</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Rocha+AS%22">Rocha AS</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Tardito+S%22">Tardito S</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Sumpton+D%22">Sumpton D</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK.<br /><searchLink fieldCode="AU" term="%22Le+Quesne+J%22">Le Quesne J</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; Department of Histopathology, Queen Elizabeth University Hospital, NHS Greater Glasgow and Clyde, UK.<br /><searchLink fieldCode="AU" term="%22Bushell+M%22">Bushell M</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Sansom+OJ%22">Sansom OJ</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK.<br /><searchLink fieldCode="AU" term="%22Bird+TG%22">Bird TG</searchLink>; Cancer Research UK Beatson Institute, Glasgow, G61 1BD, UK; School of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Glasgow, G61 1QH, UK; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, EH164TJ, UK. Electronic address: t.bird@beatson.gla.ac.uk.
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        Value: 10.1016/j.jhep.2023.01.009
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