CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer.

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Title: CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer.
Authors: Faraoni EY; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Singh K; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Chandra V; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas., Le Roux O; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas., Dai Y; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas., Sahin I; Department of Engineering, Texas Southern University, Houston, Texas., O'Brien BJ; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Strickland LN; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Li L; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas., Vucic E; Departments of Biochemistry and Molecular Pharmacology and Medicine, NYU Langone School of Medicine, New York, New York., Warner AN; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas., Pruski M; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Clark T; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Van Buren G; Division of Surgical Oncology, Baylor College of Medicine, Houston, Texas., Thosani NC; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Interventional Gastroenterology at UTHealth (iGUT), McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Bynon JS; Department of Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Wray CJ; Department of Surgery, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Bar-Sagi D; Department of Engineering, Texas Southern University, Houston, Texas., Poulsen KL; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Vornik LA; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas., Savage MI; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas., Sei S; Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland., Mohammed A; Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland., Zhao Z; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas., Brown PH; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mills T; Department of Biochemistry, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., Eltzschig HK; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas., McAllister F; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas.; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Bailey-Lundberg JM; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Interventional Gastroenterology at UTHealth (iGUT), McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
Source: Cancer research [Cancer Res] 2023 Apr 04; Vol. 83 (7), pp. 1111-1127.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
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  Data: CD73-Dependent Adenosine Signaling through Adora2b Drives Immunosuppression in Ductal Pancreatic Cancer.
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Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Pruski+M%22">Pruski M</searchLink>; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Clark+T%22">Clark T</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Van+Buren+G%22">Van Buren G</searchLink>; Division of Surgical Oncology, Baylor College of Medicine, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Thosani+NC%22">Thosani NC</searchLink>; 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Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Vornik+LA%22">Vornik LA</searchLink>; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Savage+MI%22">Savage MI</searchLink>; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sei+S%22">Sei S</searchLink>; Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Mohammed+A%22">Mohammed A</searchLink>; Division of Cancer Prevention, National Cancer Institute, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Brown+PH%22">Brown PH</searchLink>; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Mills+T%22">Mills T</searchLink>; Department of Biochemistry, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Eltzschig+HK%22">Eltzschig HK</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22McAllister+F%22">McAllister F</searchLink>; Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas.; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Immunology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Bailey-Lundberg+JM%22">Bailey-Lundberg JM</searchLink>; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; The Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, and The University of Texas Health Science Center at Houston, Houston, Texas.; Division of Gastroenterology, Hepatology, and Nutrition, Department of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Interventional Gastroenterology at UTHealth (iGUT), McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.; Center for Perioperative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas.
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