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WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.

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Title: WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma.
Authors: Mitchell K; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA., Sprowls SA; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA., Arora S; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA., Shakya S; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Silver DJ; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA., Goins CM; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA; lathiaj@ccf.org christopher.hubert@case.edu., Wallace L; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Roversi G; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA., Schafer RE; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA., Kay K; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Miller TE; Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.; Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA., Lauko A; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA.; Department of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA.; Medical Scientist Training Program, Case Western Reserve University School of Medicine, Cleveland, Ohio 44106, USA., Bassett J; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA., Kashyap A; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., D'Amato Kass J; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Mulkearns-Hubert EE; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA., Johnson S; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Alvarado J; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Rich JN; University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA., Holland EC; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA., Paddison PJ; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA., Patel AP; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA.; Department of Neurological Surgery, University of Washington, Seattle, Washington 98195, USA., Stauffer SR; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA., Hubert CG; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA., Lathia JD; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA; lathiaj@ccf.org christopher.hubert@case.edu.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA.; Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio 44106, USA.
Source: Genes & development [Genes Dev] 2023 Feb 01; Vol. 37 (3-4), pp. 86-102. Date of Electronic Publication: 2023 Feb 02.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Mitchell+K%22">Mitchell K</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Sprowls+SA%22">Sprowls SA</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Arora+S%22">Arora S</searchLink>; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA.<br /><searchLink fieldCode="AU" term="%22Shakya+S%22">Shakya S</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Silver+DJ%22">Silver DJ</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; 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Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+S%22">Johnson S</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Alvarado+J%22">Alvarado J</searchLink>; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Rich+JN%22">Rich JN</searchLink>; University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA.<br /><searchLink fieldCode="AU" term="%22Holland+EC%22">Holland EC</searchLink>; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA.<br /><searchLink fieldCode="AU" term="%22Paddison+PJ%22">Paddison PJ</searchLink>; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA.<br /><searchLink fieldCode="AU" term="%22Patel+AP%22">Patel AP</searchLink>; Human Biology Division, Fred Hutchinson Cancer Center, Seattle, Washington 98109, USA.; Department of Neurological Surgery, University of Washington, Seattle, Washington 98195, USA.<br /><searchLink fieldCode="AU" term="%22Stauffer+SR%22">Stauffer SR</searchLink>; Center for Therapeutics Discovery, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Hubert+CG%22">Hubert CG</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA.<br /><searchLink fieldCode="AU" term="%22Lathia+JD%22">Lathia JD</searchLink>; Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44106, USA; lathiaj@ccf.org christopher.hubert@case.edu.; Case Comprehensive Cancer Center, Cleveland, Ohio 44106, USA.; Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio 44106, USA.; Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio 44106, USA.
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  Data: <searchLink fieldCode="JN" term="%228711660%22">Genes & development</searchLink> [Genes Dev] 2023 Feb 01; Vol. 37 (3-4), pp. 86-102. <i>Date of Electronic Publication: </i>2023 Feb 02.
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