Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence.
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| Title: | Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence. |
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| Authors: | Razvi E; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Whitfield GB; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.; Département de Microbiologie, Infectiologie, et Immunologie, Faculté de Médecine Université de Montréal, Montréal, QC, Canada., Reichhardt C; Department of Microbiology, University of Washington, Seattle, WA, USA.; Department of Chemistry, Washington University, St. Louis, MO, USA., Dreifus JE; Department of Microbiology, University of Washington, Seattle, WA, USA., Willis AR; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Gluscencova OB; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada., Gloag ES; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Department of Biomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine, Virginia Tech, VA, 24061, USA., Awad TS; Department of Materials Science and Engineering, University of Toronto, Toronto, ON, Canada., Rich JD; Department of Biological Sciences, University of Calgary, Calgary, AB, Canada., da Silva DP; Department of Microbiology, University of Washington, Seattle, WA, USA.; BioVectra Inc. 11 Aviation, Charlottetown, PE, Canada., Bond W; Department of Microbiology, University of Washington, Seattle, WA, USA., Le Mauff F; Department of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, QC, Canada.; Infectious Disease and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; McGill Interdisciplinary Initiative in Infection and Immunity, Montreal, QC, Canada., Sheppard DC; Department of Microbiology and Immunology, Faculty of Medicine, McGill University, Montreal, QC, Canada.; Infectious Disease and Immunity in Global Health, Research Institute of the McGill University Health Centre, Montreal, QC, Canada.; McGill Interdisciplinary Initiative in Infection and Immunity, Montreal, QC, Canada., Hatton BD; Department of Materials Science and Engineering, University of Toronto, Toronto, ON, Canada., Stoodley P; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Department of Orthopedics, The Ohio State University, Columbus, OH, 43210, USA.; National Biofilm Innovation Centre (NBIC) and National Centre for Advanced Tribology at Southampton (nCATS), University of Southampton, Southampton, SO17 1BJ, UK.; Department of Microbiology, The Ohio State University, Columbus, OH, 43210, USA., Reinke AW; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Boulianne GL; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.; Program in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada., Wozniak DJ; Department of Microbial Infection and Immunity, The Ohio State University, Columbus, OH, 43210, USA.; Department of Microbiology, The Ohio State University, Columbus, OH, 43210, USA., Harrison JJ; Department of Biological Sciences, University of Calgary, Calgary, AB, Canada., Parsek MR; Department of Microbiology, University of Washington, Seattle, WA, USA., Howell PL; Program in Molecular Medicine, The Hospital for Sick Children, Toronto, ON, Canada. howell@sickkids.ca.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada. howell@sickkids.ca. |
| Source: | NPJ biofilms and microbiomes [NPJ Biofilms Microbiomes] 2023 Feb 02; Vol. 9 (1), pp. 7. Date of Electronic Publication: 2023 Feb 02. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101666944 Publication Model: Electronic Cited Medium: Internet ISSN: 2055-5008 (Electronic) Linking ISSN: 20555008 NLM ISO Abbreviation: NPJ Biofilms Microbiomes Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2055-5008 |
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| DOI: | 10.1038/s41522-023-00375-7 |
