High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial.

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Title: High- or low-dose preoperative ipilimumab plus nivolumab in stage III urothelial cancer: the phase 1B NABUCCO trial.
Authors: van Dorp J; Department of Molecular Carcinogenesis, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands., Pipinikas C; Inivata Ltd., Babraham Research Park, Cambridge, UK., Suelmann BBM; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Mehra N; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands., van Dijk N; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Marsico G; Inivata Ltd., Babraham Research Park, Cambridge, UK., van Montfoort ML; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Hackinger S; Inivata Ltd., Babraham Research Park, Cambridge, UK., Braaf LM; Core Facility Molecular Pathology & Biobanking, Netherlands Cancer Institute, Amsterdam, The Netherlands., Amarante T; Inivata Ltd., Babraham Research Park, Cambridge, UK., van Steenis C; Genomics Core Facility, Netherlands Cancer Institute, Amsterdam, The Netherlands., McLay K; Inivata Ltd., Babraham Research Park, Cambridge, UK., Daletzakis A; Department of Biometrics, Netherlands Cancer Institute, Amsterdam, The Netherlands., van den Broek D; Department of Laboratory Medicine, Netherlands Cancer Institute, Amsterdam, The Netherlands., van de Kamp MW; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Surgical Oncology (Urology), Netherlands Cancer Institute, Amsterdam, The Netherlands., Hendricksen K; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Surgical Oncology (Urology), Netherlands Cancer Institute, Amsterdam, The Netherlands., de Feijter JM; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Boellaard TN; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Radiology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Meijer RP; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Urological Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., van der Heijden AG; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Urology, Radboud University Medical Center, Nijmegen, The Netherlands., Rosenfeld N; Inivata Ltd., Babraham Research Park, Cambridge, UK.; Cancer Research UK Cambridge Institute, Cambridge, UK.; Cancer Research UK Major Centre Cambridge, Cancer Research UK Cambridge Institute, Cambridge, UK., van Rhijn BWG; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands.; Department of Surgical Oncology (Urology), Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Urology, Caritas St. Josef Medical Centre, University of Regensburg, Regensburg, Germany., Jones G; Inivata Ltd., Babraham Research Park, Cambridge, UK. greg.jones@inivata.com., van der Heijden MS; Dutch Uro-Oncology Study Group, Bilthoven, The Netherlands. ms.vd.heijden@nki.nl.; Department of Medical Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands. ms.vd.heijden@nki.nl.
Source: Nature medicine [Nat Med] 2023 Mar; Vol. 29 (3), pp. 588-592. Date of Electronic Publication: 2023 Feb 02.
Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-170X
DOI:10.1038/s41591-022-02199-y