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Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.

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Title: Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.
Authors: Zhang Q; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Linke V; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; IMol Polish Academy of Sciences, Warsaw, Poland.; ReMedy International Research Agenda Unit, IMol Polish Academy of Sciences, Warsaw, Poland., Overmyer KA; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA., Traeger LL; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Kasahara K; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Miller IJ; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Manson DE; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Polaske TJ; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Kerby RL; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Kemis JH; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Trujillo EA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Reddy TR; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Russell JD; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Schueler KL; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Stapleton DS; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Rabaglia ME; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Seldin M; Departments of Microbiology, Immunology and Molecular Genetics, and Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Gatti DM; The Jackson Laboratory, Bar Harbor, ME, USA., Keele GR; The Jackson Laboratory, Bar Harbor, ME, USA., Pham DT; The Jackson Laboratory, Bar Harbor, ME, USA., Gerdt JP; Department of Chemistry, Indiana University, Bloomington, IN, USA., Vivas EI; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA., Lusis AJ; Departments of Microbiology, Immunology and Molecular Genetics, and Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.; Department of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Keller MP; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Churchill GA; The Jackson Laboratory, Bar Harbor, ME, USA., Blackwell HE; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA., Broman KW; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA., Attie AD; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI, USA., Coon JJ; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA.; Morgridge Institute for Research, Madison, WI, USA., Rey FE; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI, USA. ferey@wisc.edu.
Source: Nature microbiology [Nat Microbiol] 2023 Mar; Vol. 8 (3), pp. 424-440. Date of Electronic Publication: 2023 Feb 09.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
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