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PARP1 associates with R-loops to promote their resolution and genome stability.

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Title: PARP1 associates with R-loops to promote their resolution and genome stability.
Authors: Laspata N; UPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Pittsburgh, PA 15213, USA.; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA., Kaur P; Physics Department, Raleigh, NC 27695, USA.; Center for Human Health and the Environment, Raleigh, NC 27695, USA., Mersaoui SY; CHU de Québec Research Centre, HDQ Pavilion, Oncology Division, Laval University Cancer Research Center, McMahon, Québec City, Québec G1R 3S3, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec, Canada., Muoio D; UPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Pittsburgh, PA 15213, USA., Liu ZS; Department of Pharmacology, The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Bannister MH; Department of Pharmacology, The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Nguyen HD; Department of Pharmacology, The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA., Curry C; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA., Pascal JM; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec H3C 3J7, Canada., Poirier GG; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec, Canada.; CHU de Québec Research Centre, CHUL Pavilion, Oncology Division, Quebec, Canada., Wang H; Physics Department, Raleigh, NC 27695, USA.; Center for Human Health and the Environment, Raleigh, NC 27695, USA.; Toxicology Program, North Carolina State University, Raleigh, NC, USA., Masson JY; CHU de Québec Research Centre, HDQ Pavilion, Oncology Division, Laval University Cancer Research Center, McMahon, Québec City, Québec G1R 3S3, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec, Canada., Fouquerel E; UPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Pittsburgh, PA 15213, USA.
Source: Nucleic acids research [Nucleic Acids Res] 2023 Mar 21; Vol. 51 (5), pp. 2215-2237.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Laspata+N%22">Laspata N</searchLink>; UPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Pittsburgh, PA 15213, USA.; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.<br /><searchLink fieldCode="AU" term="%22Kaur+P%22">Kaur P</searchLink>; Physics Department, Raleigh, NC 27695, USA.; Center for Human Health and the Environment, Raleigh, NC 27695, USA.<br /><searchLink fieldCode="AU" term="%22Mersaoui+SY%22">Mersaoui SY</searchLink>; CHU de Québec Research Centre, HDQ Pavilion, Oncology Division, Laval University Cancer Research Center, McMahon, Québec City, Québec G1R 3S3, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Muoio+D%22">Muoio D</searchLink>; UPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Pittsburgh, PA 15213, USA.<br /><searchLink fieldCode="AU" term="%22Liu+ZS%22">Liu ZS</searchLink>; Department of Pharmacology, The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Bannister+MH%22">Bannister MH</searchLink>; Department of Pharmacology, The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+HD%22">Nguyen HD</searchLink>; Department of Pharmacology, The Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.<br /><searchLink fieldCode="AU" term="%22Curry+C%22">Curry C</searchLink>; Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.<br /><searchLink fieldCode="AU" term="%22Pascal+JM%22">Pascal JM</searchLink>; Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec H3C 3J7, Canada.<br /><searchLink fieldCode="AU" term="%22Poirier+GG%22">Poirier GG</searchLink>; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec, Canada.; CHU de Québec Research Centre, CHUL Pavilion, Oncology Division, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Physics Department, Raleigh, NC 27695, USA.; Center for Human Health and the Environment, Raleigh, NC 27695, USA.; Toxicology Program, North Carolina State University, Raleigh, NC, USA.<br /><searchLink fieldCode="AU" term="%22Masson+JY%22">Masson JY</searchLink>; CHU de Québec Research Centre, HDQ Pavilion, Oncology Division, Laval University Cancer Research Center, McMahon, Québec City, Québec G1R 3S3, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Université Laval, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Fouquerel+E%22">Fouquerel E</searchLink>; UPMC Hillman Cancer Center, University of Pittsburgh Cancer Institute, Department of Pharmacology and Chemical Biology, Pittsburgh, PA 15213, USA.
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