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Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production.

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Title: Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production.
Authors: Cantoni E; Vita-Salute San Raffaele University, Milan, Italy., Merelli I; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, Milan, Italy.; National Research Council, Institute for Biomedical Technologies, Segrate, Italy., Stefanoni D; Vita-Salute San Raffaele University, Milan, Italy.; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, USA., Tomelleri A; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Campochiaro C; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Giordano V; Vita-Salute San Raffaele University, Milan, Italy., Panigada M; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Baldissera EM; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Merlo Pich L; Vita-Salute San Raffaele University, Milan, Italy., Natoli V; University of Genova and IRCCS G. Gaslini Institute, Genoa, Italy., Ziogas A; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands., Domínguez-Andrés J; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands., De Luca G; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Mazza D; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Zambrano S; Vita-Salute San Raffaele University, Milan, Italy.; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Gnani D; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ferrarini M; Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ferrero E; Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Agresti A; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Vergani B; Department of Pathology, Bicocca University, Milan, Italy., Leone BE; Department of Pathology, Bicocca University, Milan, Italy., Cenci S; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Ravelli A; University of Genova and IRCCS G. Gaslini Institute, Genoa, Italy., Matucci-Cerinic M; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.; Department Experimental and Clinical Medicine and Division of Rheumatology AOUC, University of Florence, Florence, Italy., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, USA., Joosten LAB; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.; Department of Medical Genetics, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania., Dagna L; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy., Netea MG; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany., Molteni R; Vita-Salute San Raffaele University, Milan, Italy.; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy., Cavalli G; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Source: Rheumatology (Oxford, England) [Rheumatology (Oxford)] 2023 Oct 03; Vol. 62 (10), pp. 3469-3479.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100883501 Publication Model: Print Cited Medium: Internet ISSN: 1462-0332 (Electronic) Linking ISSN: 14620324 NLM ISO Abbreviation: Rheumatology (Oxford) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Myelomonocytic cells in giant cell arteritis activate trained immunity programs sustaining inflammation and cytokine production.
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  Data: <searchLink fieldCode="AU" term="%22Cantoni+E%22">Cantoni E</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Merelli+I%22">Merelli I</searchLink>; San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, Milan, Italy.; National Research Council, Institute for Biomedical Technologies, Segrate, Italy.<br /><searchLink fieldCode="AU" term="%22Stefanoni+D%22">Stefanoni D</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Tomelleri+A%22">Tomelleri A</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Campochiaro+C%22">Campochiaro C</searchLink>; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Giordano+V%22">Giordano V</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Panigada+M%22">Panigada M</searchLink>; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Baldissera+EM%22">Baldissera EM</searchLink>; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Merlo+Pich+L%22">Merlo Pich L</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Natoli+V%22">Natoli V</searchLink>; University of Genova and IRCCS G. Gaslini Institute, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Ziogas+A%22">Ziogas A</searchLink>; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Domínguez-Andrés+J%22">Domínguez-Andrés J</searchLink>; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22De+Luca+G%22">De Luca G</searchLink>; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mazza+D%22">Mazza D</searchLink>; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Zambrano+S%22">Zambrano S</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gnani+D%22">Gnani D</searchLink>; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrarini+M%22">Ferrarini M</searchLink>; Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrero+E%22">Ferrero E</searchLink>; Division of Experimental Oncology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Agresti+A%22">Agresti A</searchLink>; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Vergani+B%22">Vergani B</searchLink>; Department of Pathology, Bicocca University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Leone+BE%22">Leone BE</searchLink>; Department of Pathology, Bicocca University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cenci+S%22">Cenci S</searchLink>; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ravelli+A%22">Ravelli A</searchLink>; University of Genova and IRCCS G. Gaslini Institute, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Matucci-Cerinic+M%22">Matucci-Cerinic M</searchLink>; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.; Department Experimental and Clinical Medicine and Division of Rheumatology AOUC, University of Florence, Florence, Italy.<br /><searchLink fieldCode="AU" term="%22D'Alessandro+A%22">D'Alessandro A</searchLink>; Department of Biochemistry and Molecular Genetics, University of Colorado, Denver, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Joosten+LAB%22">Joosten LAB</searchLink>; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.; Department of Medical Genetics, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.<br /><searchLink fieldCode="AU" term="%22Dagna+L%22">Dagna L</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Netea+MG%22">Netea MG</searchLink>; Department of Internal Medicine and Radboud Center for Infectious diseases (RCI), Radboud University Nijmegen Medical Centre, Nijmegen, the Netherlands.; Department of Immunology and Metabolism, Life and Medical Sciences Institute, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Molteni+R%22">Molteni R</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cavalli+G%22">Cavalli G</searchLink>; Vita-Salute San Raffaele University, Milan, Italy.; Unit of Immunology, Rheumatology, Allergy, and Rare Diseases, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.; Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy.
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