An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil.
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| Title: | An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil. |
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| Authors: | D'Angelo E; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy., Pastrello C; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada., Biccari A; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy., Marangio A; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy., Sensi F; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy.; Department of Women and Children's Health, University of Padova, Padua, Italy., Crotti S; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy., Fassan M; Department of Medicine, University of Padua, Padova, Italy.; Veneto Institute of Oncology-Institute for Hospitalization and Care Scientific, Padova, Italy., Jurisica I; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Medical Biophysics and Computer Science, and Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia., Pucciarelli S; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy., Agostini M; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy. |
| Source: | International journal of cancer [Int J Cancer] 2023 Jul 15; Vol. 153 (2), pp. 437-449. Date of Electronic Publication: 2023 Mar 23. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36815540 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22D'Angelo+E%22">D'Angelo E</searchLink>; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Pastrello+C%22">Pastrello C</searchLink>; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Biccari+A%22">Biccari A</searchLink>; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Marangio+A%22">Marangio A</searchLink>; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Sensi+F%22">Sensi F</searchLink>; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy.; Department of Women and Children's Health, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Crotti+S%22">Crotti S</searchLink>; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Fassan+M%22">Fassan M</searchLink>; Department of Medicine, University of Padua, Padova, Italy.; Veneto Institute of Oncology-Institute for Hospitalization and Care Scientific, Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Jurisica+I%22">Jurisica I</searchLink>; Osteoarthritis Research Program, Division of Orthopedic Surgery, Schroeder Arthritis Institute and Data Science Discovery Centre for Chronic Diseases, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada.; Department of Medical Biophysics and Computer Science, and Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada.; Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia.<br /><searchLink fieldCode="AU" term="%22Pucciarelli+S%22">Pucciarelli S</searchLink>; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Agostini+M%22">Agostini M</searchLink>; General Surgery 3, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padua, Italy.; LIFELAB Program, Consorzio per la Ricerca Sanitaria-CORIS, Padova, Italy.; NanoInspired biomedicine lab, Fondazione Istituto di Ricerca Pediatrica Città della Speranza, Padua, Italy. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220042124%22">International journal of cancer</searchLink> [Int J Cancer] 2023 Jul 15; Vol. 153 (2), pp. 437-449. <i>Date of Electronic Publication: </i>2023 Mar 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Liss%22">Wiley-Liss </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0042124 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-0215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200207136%22">00207136 </searchLink><i>NLM ISO Abbreviation: </i>Int J Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36815540 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/ijc.34478 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 437 Titles: – TitleFull: An integrated multiomics analysis of rectal cancer patients identified POU2F3 as a putative druggable target and entinostat as a cytotoxic enhancer of 5-fluorouracil. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: D'Angelo E – PersonEntity: Name: NameFull: Pastrello C – PersonEntity: Name: NameFull: Biccari A – PersonEntity: Name: NameFull: Marangio A – PersonEntity: Name: NameFull: Sensi F – PersonEntity: Name: NameFull: Crotti S – PersonEntity: Name: NameFull: Fassan M – PersonEntity: Name: NameFull: Jurisica I – PersonEntity: Name: NameFull: Pucciarelli S – PersonEntity: Name: NameFull: Agostini M IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 07 Text: 2023 Jul 15 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1097-0215 Numbering: – Type: volume Value: 153 – Type: issue Value: 2 Titles: – TitleFull: International journal of cancer Type: main |
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