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Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations - A nationwide trial.

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Title: Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations - A nationwide trial.
Authors: Harbers VEM; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., Zwerink LGJM; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands., Rongen GA; Department of Internal Medicine and Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands., Klein WM; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., van der Vleuten CJM; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.; VASCERN ERN on Rare Multisystemic Vascular Diseases, Healthcare Provider Coordinator: Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Centre de Réference (CRMR) Syndromes de Marfan et apparentés, Paris, France., van Rijnsoever IMP; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pediatrics, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands., Gerdsen-Drury L; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands., Flucke UE; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., Verhoeven BH; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands., de Laat PCJ; Department of Pediatric Oncology, WEVAR-Team Rotterdam Erasmus MC-Sophia, Rotterdam, The Netherlands., van der Horst CMAM; Department of Plastic Reconstructive and Hand Surgery, AVA-Team, Amsterdam University Medical Center, Amsterdam, The Netherlands., Schultze Kool LJ; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; VASCERN ERN on Rare Multisystemic Vascular Diseases, Healthcare Provider Coordinator: Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Centre de Réference (CRMR) Syndromes de Marfan et apparentés, Paris, France., Te Loo DMWM; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pediatric Hematology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.
Source: Clinical and translational science [Clin Transl Sci] 2023 May; Vol. 16 (5), pp. 781-796. Date of Electronic Publication: 2023 Feb 23.
Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Clinical differences in sirolimus treatment with low target levels between children and adults with vascular malformations - A nationwide trial.
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  Data: <searchLink fieldCode="AU" term="%22Harbers+VEM%22">Harbers VEM</searchLink>; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zwerink+LGJM%22">Zwerink LGJM</searchLink>; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rongen+GA%22">Rongen GA</searchLink>; Department of Internal Medicine and Pharmacology-Toxicology, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Klein+WM%22">Klein WM</searchLink>; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Vleuten+CJM%22">van der Vleuten CJM</searchLink>; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Dermatology, Radboud University Medical Center, Nijmegen, The Netherlands.; VASCERN ERN on Rare Multisystemic Vascular Diseases, Healthcare Provider Coordinator: Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Centre de Réference (CRMR) Syndromes de Marfan et apparentés, Paris, France.<br /><searchLink fieldCode="AU" term="%22van+Rijnsoever+IMP%22">van Rijnsoever IMP</searchLink>; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pediatrics, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gerdsen-Drury+L%22">Gerdsen-Drury L</searchLink>; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Flucke+UE%22">Flucke UE</searchLink>; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verhoeven+BH%22">Verhoeven BH</searchLink>; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Surgery, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Laat+PCJ%22">de Laat PCJ</searchLink>; Department of Pediatric Oncology, WEVAR-Team Rotterdam Erasmus MC-Sophia, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Horst+CMAM%22">van der Horst CMAM</searchLink>; Department of Plastic Reconstructive and Hand Surgery, AVA-Team, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Schultze+Kool+LJ%22">Schultze Kool LJ</searchLink>; Department of Medical Imaging, Radboud University Medical Center, Nijmegen, The Netherlands.; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; VASCERN ERN on Rare Multisystemic Vascular Diseases, Healthcare Provider Coordinator: Assistance Publique-Hôpitaux de Paris, Hôpital Bichat-Claude Bernard, Centre de Réference (CRMR) Syndromes de Marfan et apparentés, Paris, France.<br /><searchLink fieldCode="AU" term="%22Te+Loo+DMWM%22">Te Loo DMWM</searchLink>; Radboudumc Center of Expertise HECOVAN, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Pediatric Hematology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101474067%22">Clinical and translational science</searchLink> [Clin Transl Sci] 2023 May; Vol. 16 (5), pp. 781-796. <i>Date of Electronic Publication: </i>2023 Feb 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22WileyBlackwell+Pub%22">WileyBlackwell Pub </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101474067 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1752-8062 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217528054%22">17528054 </searchLink><i>NLM ISO Abbreviation: </i>Clin Transl Sci <i>Subsets: </i>MEDLINE
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