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Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo.

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Title: Degradable Bottlebrush Polypeptides and the Impact of their Architecture on Cell Uptake, Pharmacokinetics, and Biodistribution In Vivo.
Authors: Strasser P; Institute of Polymer Chemistry, Johannes Kepler University Linz, Linz, 4040, Austria., Montsch B; Center for Cancer Research and Comprehensive Cancer Center, Medical University Vienna, Vienna, 1090, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Vienna, 1090, Austria., Weiss S; Laboratory of Macromolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, Vienna, 1090, Austria., Sami H; Laboratory of Macromolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, Vienna, 1090, Austria., Kugler C; Laboratory of Macromolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, Vienna, 1090, Austria., Hager S; Center for Cancer Research and Comprehensive Cancer Center, Medical University Vienna, Vienna, 1090, Austria.; Department of Food Chemistry and Toxicology, Faculty of Chemistry, University of Vienna, Vienna, 1090, Austria., Schueffl H; Center for Cancer Research and Comprehensive Cancer Center, Medical University Vienna, Vienna, 1090, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Vienna, 1090, Austria., Mader R; Department of Medicine I, Medical University of Vienna, Vienna, 1090, Austria., Brüggemann O; Institute of Polymer Chemistry, Johannes Kepler University Linz, Linz, 4040, Austria., Kowol CR; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Vienna, 1090, Austria.; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Vienna, 1090, Austria., Ogris M; Laboratory of Macromolecular Cancer Therapeutics (MMCT), Department of Pharmaceutical Sciences, Faculty of Life Sciences, University of Vienna, Vienna, 1090, Austria., Heffeter P; Center for Cancer Research and Comprehensive Cancer Center, Medical University Vienna, Vienna, 1090, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Vienna, 1090, Austria., Teasdale I; Institute of Polymer Chemistry, Johannes Kepler University Linz, Linz, 4040, Austria.
Source: Small (Weinheim an der Bergstrasse, Germany) [Small] 2023 Jun; Vol. 19 (22), pp. e2300767. Date of Electronic Publication: 2023 Feb 26.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101235338 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1613-6829 (Electronic) Linking ISSN: 16136810 NLM ISO Abbreviation: Small Subsets: MEDLINE
Database: MEDLINE Ultimate
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