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Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice.

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Title: Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice.
Authors: Ramos da Silva J; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Bitencourt Rodrigues K; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Formoso Pelegrin G; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Silva Sales N; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Muramatsu H; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., de Oliveira Silva M; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Porchia BFMM; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; Laboratory of Tumor Immunology, Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, SP 05508-000, Brazil.; ImunoTera Soluções Terapêuticas Ltda., São Paulo, SP 05508-000, Brazil., Moreno ACR; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Aps LRMM; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; ImunoTera Soluções Terapêuticas Ltda., São Paulo, SP 05508-000, Brazil., Venceslau-Carvalho AA; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Tombácz I; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Fotoran WL; Department of Parasitology, Institute for Biomedical Sciences, University of São Paulo, SP 05508-000, Brazil., Karikó K; BioNTech SE, Mainz, 55131, Germany., Lin PJC; Acuitas Therapeutics, Vancouver, BC V6T1Z3, Canada., Tam YK; Acuitas Therapeutics, Vancouver, BC V6T1Z3, Canada., de Oliveira Diniz M; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil., Pardi N; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., de Souza Ferreira LC; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; Scientific Platform Pasteur USP, University of São Paulo, São Paulo, SP, 05508-020, Brazil.
Source: Science translational medicine [Sci Transl Med] 2023 Mar 08; Vol. 15 (686), pp. eabn3464. Date of Electronic Publication: 2023 Mar 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice.
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  Data: <searchLink fieldCode="AU" term="%22Ramos+da+Silva+J%22">Ramos da Silva J</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Bitencourt+Rodrigues+K%22">Bitencourt Rodrigues K</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Formoso+Pelegrin+G%22">Formoso Pelegrin G</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Silva+Sales+N%22">Silva Sales N</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Muramatsu+H%22">Muramatsu H</searchLink>; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+Silva+M%22">de Oliveira Silva M</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Porchia+BFMM%22">Porchia BFMM</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; Laboratory of Tumor Immunology, Department of Immunology, Biomedical Sciences Institute, University of São Paulo, São Paulo, SP 05508-000, Brazil.; ImunoTera Soluções Terapêuticas Ltda., São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Moreno+ACR%22">Moreno ACR</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Aps+LRMM%22">Aps LRMM</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; ImunoTera Soluções Terapêuticas Ltda., São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Venceslau-Carvalho+AA%22">Venceslau-Carvalho AA</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Tombácz+I%22">Tombácz I</searchLink>; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Fotoran+WL%22">Fotoran WL</searchLink>; Department of Parasitology, Institute for Biomedical Sciences, University of São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Karikó+K%22">Karikó K</searchLink>; BioNTech SE, Mainz, 55131, Germany.<br /><searchLink fieldCode="AU" term="%22Lin+PJC%22">Lin PJC</searchLink>; Acuitas Therapeutics, Vancouver, BC V6T1Z3, Canada.<br /><searchLink fieldCode="AU" term="%22Tam+YK%22">Tam YK</searchLink>; Acuitas Therapeutics, Vancouver, BC V6T1Z3, Canada.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+Diniz+M%22">de Oliveira Diniz M</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.<br /><searchLink fieldCode="AU" term="%22Pardi+N%22">Pardi N</searchLink>; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22de+Souza+Ferreira+LC%22">de Souza Ferreira LC</searchLink>; Vaccine Development Laboratory, Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP 05508-000, Brazil.; Scientific Platform Pasteur USP, University of São Paulo, São Paulo, SP, 05508-020, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2023 Mar 08; Vol. 15 (686), pp. eabn3464. <i>Date of Electronic Publication: </i>2023 Mar 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE
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        Value: 10.1126/scitranslmed.abn3464
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