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A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.

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Title: A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.
Authors: Ryan FJ; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia., Norton TS; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia., McCafferty C; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia., Blake SJ; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia., Stevens NE; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia., James J; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia., Eden GL; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia., Tee YC; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia., Benson SC; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia., Masavuli MG; Viral Immunology Group, Adelaide Medical School, University of Adelaide and Basil Hetzel Institute for Translational Health Research, Adelaide, SA 5011, Australia., Yeow AEL; Viral Immunology Group, Adelaide Medical School, University of Adelaide and Basil Hetzel Institute for Translational Health Research, Adelaide, SA 5011, Australia., Abayasingam A; School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW 2052, Australia; The Kirby Institute, Sydney, NSW 2052, Australia., Agapiou D; The Kirby Institute, Sydney, NSW 2052, Australia., Stevens H; Clinical Haematology Department, Alfred Hospital, Melbourne, VIC 3004, Australia; Australian Centre for Blood Diseases, Monash University, Melbourne, VIC 3800, Australia., Zecha J; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, R&D, AstraZeneca, Gaithersburg, MD 20878, USA., Messina NL; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia; Infectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia., Curtis N; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia; Infectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia., Ignjatovic V; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia., Monagle P; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia., Tran H; Clinical Haematology Department, Alfred Hospital, Melbourne, VIC 3004, Australia; Australian Centre for Blood Diseases, Monash University, Melbourne, VIC 3800, Australia., McFadyen JD; Clinical Haematology Department, Alfred Hospital, Melbourne, VIC 3004, Australia; Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, VIC 3010, Australia., Bull RA; School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW 2052, Australia; The Kirby Institute, Sydney, NSW 2052, Australia., Grubor-Bauk B; Viral Immunology Group, Adelaide Medical School, University of Adelaide and Basil Hetzel Institute for Translational Health Research, Adelaide, SA 5011, Australia., Lynn MA; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia., Botten R; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia., Barry SE; Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, SA 5000, Australia., Lynn DJ; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia. Electronic address: david.lynn@sahmri.com.
Source: Cell reports. Medicine [Cell Rep Med] 2023 Mar 21; Vol. 4 (3), pp. 100971. Date of Electronic Publication: 2023 Feb 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: A systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA and adenovirus vectored vaccines.
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  Data: <searchLink fieldCode="AU" term="%22Ryan+FJ%22">Ryan FJ</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.<br /><searchLink fieldCode="AU" term="%22Norton+TS%22">Norton TS</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia.<br /><searchLink fieldCode="AU" term="%22McCafferty+C%22">McCafferty C</searchLink>; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Blake+SJ%22">Blake SJ</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.<br /><searchLink fieldCode="AU" term="%22Stevens+NE%22">Stevens NE</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.<br /><searchLink fieldCode="AU" term="%22James+J%22">James J</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia.<br /><searchLink fieldCode="AU" term="%22Eden+GL%22">Eden GL</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia.<br /><searchLink fieldCode="AU" term="%22Tee+YC%22">Tee YC</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.<br /><searchLink fieldCode="AU" term="%22Benson+SC%22">Benson SC</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.<br /><searchLink fieldCode="AU" term="%22Masavuli+MG%22">Masavuli MG</searchLink>; Viral Immunology Group, Adelaide Medical School, University of Adelaide and Basil Hetzel Institute for Translational Health Research, Adelaide, SA 5011, Australia.<br /><searchLink fieldCode="AU" term="%22Yeow+AEL%22">Yeow AEL</searchLink>; Viral Immunology Group, Adelaide Medical School, University of Adelaide and Basil Hetzel Institute for Translational Health Research, Adelaide, SA 5011, Australia.<br /><searchLink fieldCode="AU" term="%22Abayasingam+A%22">Abayasingam A</searchLink>; School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW 2052, Australia; The Kirby Institute, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Agapiou+D%22">Agapiou D</searchLink>; The Kirby Institute, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Stevens+H%22">Stevens H</searchLink>; Clinical Haematology Department, Alfred Hospital, Melbourne, VIC 3004, Australia; Australian Centre for Blood Diseases, Monash University, Melbourne, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22Zecha+J%22">Zecha J</searchLink>; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, R&D, AstraZeneca, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Messina+NL%22">Messina NL</searchLink>; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia; Infectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Curtis+N%22">Curtis N</searchLink>; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia; Infectious Diseases Group, Murdoch Children's Research Institute, Parkville, VIC 3052, Australia.<br /><searchLink fieldCode="AU" term="%22Ignjatovic+V%22">Ignjatovic V</searchLink>; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Monagle+P%22">Monagle P</searchLink>; Haematology Research, Murdoch Children's Research Institute, Melbourne, VIC 3052, Australia; Department of Paediatrics, University of Melbourne, Melbourne, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Tran+H%22">Tran H</searchLink>; Clinical Haematology Department, Alfred Hospital, Melbourne, VIC 3004, Australia; Australian Centre for Blood Diseases, Monash University, Melbourne, VIC 3800, Australia.<br /><searchLink fieldCode="AU" term="%22McFadyen+JD%22">McFadyen JD</searchLink>; Clinical Haematology Department, Alfred Hospital, Melbourne, VIC 3004, Australia; Atherothrombosis and Vascular Biology Program, Baker Heart and Diabetes Institute, Melbourne, VIC 3004, Australia; Baker Department of Cardiometabolic Health, The University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Bull+RA%22">Bull RA</searchLink>; School of Medical Sciences, Faculty of Medicine, UNSW, Sydney, NSW 2052, Australia; The Kirby Institute, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Grubor-Bauk+B%22">Grubor-Bauk B</searchLink>; Viral Immunology Group, Adelaide Medical School, University of Adelaide and Basil Hetzel Institute for Translational Health Research, Adelaide, SA 5011, Australia.<br /><searchLink fieldCode="AU" term="%22Lynn+MA%22">Lynn MA</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.<br /><searchLink fieldCode="AU" term="%22Botten+R%22">Botten R</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia.<br /><searchLink fieldCode="AU" term="%22Barry+SE%22">Barry SE</searchLink>; Department of Thoracic Medicine, Royal Adelaide Hospital, Adelaide, SA 5000, Australia.<br /><searchLink fieldCode="AU" term="%22Lynn+DJ%22">Lynn DJ</searchLink>; Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, SA 5001, Australia; Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia. Electronic address: david.lynn@sahmri.com.
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  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2023 Mar 21; Vol. 4 (3), pp. 100971. <i>Date of Electronic Publication: </i>2023 Feb 17.
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