Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts.

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Title: Multiomic analyses implicate a neurodevelopmental program in the pathogenesis of cerebral arachnoid cysts.
Authors: Kundishora AJ; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Allington G; Department of Pathology, Yale University School of Medicine, New Haven, CT, USA.; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA., McGee S; GeneDx, Gaithersburg, MD, USA., Mekbib KY; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA., Gainullin V; GeneDx, Gaithersburg, MD, USA., Timberlake AT; Hansjörg Wyss Department of Plastic Surgery, New York University Langone Medical Center, New York, NY, USA., Nelson-Williams C; Department of Genetics, Yale University School of Medicine, New Haven, CT, USA., Kiziltug E; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Smith H; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA.; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA., Ocken J; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Shohfi J; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Allocco A; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Duy PQ; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Elsamadicy AA; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Dong W; Laboratory of Human Genetics and Genomics, The Rockefeller University, New York, NY, USA., Zhao S; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Wang YC; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Qureshi HM; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., DiLuna ML; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Mane S; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; Yale Center for Genomic Analysis, Yale University, West Haven, CT, USA., Tikhonova IR; School of Pharmacy, Queen's University Belfast, Belfast, UK., Fu PY; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Castaldi C; Yale Center for Genomic Analysis, Yale University, West Haven, CT, USA., López-Giráldez F; Yale Center for Genomic Analysis, Yale University, West Haven, CT, USA., Knight JR; Yale Center for Genomic Analysis, Yale University, West Haven, CT, USA., Furey CG; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Carter BS; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA., Haider S; School of Pharmacy, University College London, London, UK., Moreno-De-Luca A; Department of Radiology, Autism and Developmental Medicine Institute, Genomic Medicine Institute, Geisinger, Danville, PA, USA., Alper SL; Division of Nephrology and Vascular Biology Research Center, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Gunel M; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA., Millan F; GeneDx, Gaithersburg, MD, USA., Lifton RP; Laboratory of Human Genetics and Genomics, The Rockefeller University, New York, NY, USA., Torene RI; GeneDx, Gaithersburg, MD, USA., Jin SC; Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA., Kahle KT; Department of Neurosurgery, Yale University School of Medicine, New Haven, CT, USA. kahle.kristopher@mgh.harvard.edu.; Department of Neurosurgery, Massachusetts General Hospital, Boston, MA, USA. kahle.kristopher@mgh.harvard.edu.; Division of Genetics and Genomics, Boston Children's Hospital, Boston, MA, USA. kahle.kristopher@mgh.harvard.edu.; Broad Institute of MIT and Harvard, Cambridge, MA, USA. kahle.kristopher@mgh.harvard.edu.
Source: Nature medicine [Nat Med] 2023 Mar; Vol. 29 (3), pp. 667-678. Date of Electronic Publication: 2023 Mar 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-170X
DOI:10.1038/s41591-023-02238-2