Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation.
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| Title: | Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation. |
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| Authors: | Coni S; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy. Electronic address: sonia.coni@uniroma1.it., Bordone R; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Ivy DM; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Yurtsever ZN; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Di Magno L; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., D'Amico R; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Cesaro B; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Fatica A; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy., Belardinilli F; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Bufalieri F; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Maroder M; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., De Smaele E; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy., Di Marcotullio L; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Giannini G; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy., Agostinelli E; International Polyamines Foundation-ONLUS, Via del Forte Tiburtino 98, 00159, Rome, Italy; Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 151, 00155, Rome, Italy., Canettieri G; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy; IRCCS Neuromed S.p.A., Via Atinense 18, Pozzilli, Isernia, Italy. Electronic address: gianluca.canettieri@uniroma1.it. |
| Source: | Cancer letters [Cancer Lett] 2023 Apr 10; Vol. 559, pp. 216120. Date of Electronic Publication: 2023 Mar 08. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36893894 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Coni+S%22">Coni S</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy. Electronic address: sonia.coni@uniroma1.it.<br /><searchLink fieldCode="AU" term="%22Bordone+R%22">Bordone R</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ivy+DM%22">Ivy DM</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Yurtsever+ZN%22">Yurtsever ZN</searchLink>; Department of Biochemical Sciences 'A. Rossi Fanelli', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Magno+L%22">Di Magno L</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22D'Amico+R%22">D'Amico R</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Cesaro+B%22">Cesaro B</searchLink>; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Fatica+A%22">Fatica A</searchLink>; Department of Biology and Biotechnologies 'Charles Darwin', Sapienza University of Rome, Piazzale Aldo Moro 5, 00185, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Belardinilli+F%22">Belardinilli F</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Bufalieri+F%22">Bufalieri F</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Maroder+M%22">Maroder M</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22De+Smaele+E%22">De Smaele E</searchLink>; Department of Experimental Medicine, Sapienza University, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Di+Marcotullio+L%22">Di Marcotullio L</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Giannini+G%22">Giannini G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Agostinelli+E%22">Agostinelli E</searchLink>; International Polyamines Foundation-ONLUS, Via del Forte Tiburtino 98, 00159, Rome, Italy; Department of Sense Organs, Sapienza University of Rome, Policlinico Umberto I, Viale del Policlinico 151, 00155, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Canettieri+G%22">Canettieri G</searchLink>; Department of Molecular Medicine, Sapienza University of Rome, Laboratory Affiliated to Istituto Pasteur Italia, Fondazione Cenci-Bolognetti, Viale Regina Elena 291, 00161, Rome, Italy; IRCCS Neuromed S.p.A., Via Atinense 18, Pozzilli, Isernia, Italy. Electronic address: gianluca.canettieri@uniroma1.it. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2023 Apr 10; Vol. 559, pp. 216120. <i>Date of Electronic Publication: </i>2023 Mar 08. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ireland%22">Elsevier Science Ireland </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>7600053 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1872-7980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203043835%22">03043835 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Lett <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36893894 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.canlet.2023.216120 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 216120 Titles: – TitleFull: Combined inhibition of polyamine metabolism and eIF5A hypusination suppresses colorectal cancer growth through a converging effect on MYC translation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Coni S – PersonEntity: Name: NameFull: Bordone R – PersonEntity: Name: NameFull: Ivy DM – PersonEntity: Name: NameFull: Yurtsever ZN – PersonEntity: Name: NameFull: Di Magno L – PersonEntity: Name: NameFull: D'Amico R – PersonEntity: Name: NameFull: Cesaro B – PersonEntity: Name: NameFull: Fatica A – PersonEntity: Name: NameFull: Belardinilli F – PersonEntity: Name: NameFull: Bufalieri F – PersonEntity: Name: NameFull: Maroder M – PersonEntity: Name: NameFull: De Smaele E – PersonEntity: Name: NameFull: Di Marcotullio L – PersonEntity: Name: NameFull: Giannini G – PersonEntity: Name: NameFull: Agostinelli E – PersonEntity: Name: NameFull: Canettieri G IsPartOfRelationships: – BibEntity: Dates: – D: 10 M: 04 Text: 2023 Apr 10 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1872-7980 Numbering: – Type: volume Value: 559 Titles: – TitleFull: Cancer letters Type: main |
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