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Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.

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Title: Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut.
Authors: Foley MH; Department of Pathobiology and Population Health, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA., Walker ME; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Stewart AK; Department of Chemistry, North Carolina State University, Raleigh, NC, USA., O'Flaherty S; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA., Gentry EC; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Patel S; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beaty VV; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Allen G; Department of Pathobiology and Population Health, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA., Pan M; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA., Simpson JB; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Perkins C; Department of Pathobiology and Population Health, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA., Vanhoy ME; Department of Pathobiology and Population Health, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA., Dougherty MK; Department of Pediatrics, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., McGill SK; Department of Pediatrics, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gulati AS; Department of Pediatrics, Division of Gastroenterology and Hepatology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Dorrestein PC; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, San Diego, CA, USA.; Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA, USA., Baker ES; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Chemistry, North Carolina State University, Raleigh, NC, USA., Redinbo MR; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. redinbo@unc.edu.; Departments of Biochemistry and Biophysics, and Microbiology and Immunology, and the Integrated Program in Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. redinbo@unc.edu., Barrangou R; Department of Food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, NC, USA. rbarran@ncsu.edu., Theriot CM; Department of Pathobiology and Population Health, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA. cmtherio@ncsu.edu.
Source: Nature microbiology [Nat Microbiol] 2023 Apr; Vol. 8 (4), pp. 611-628. Date of Electronic Publication: 2023 Mar 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101674869 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2058-5276 (Electronic) Linking ISSN: 20585276 NLM ISO Abbreviation: Nat Microbiol Subsets: MEDLINE
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