The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.

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Title:	The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.
Authors:	Labrousse G; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France., Vande Perre P; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France., Parra G; Center for Genomic Analysis, CNAG, Carrer de Baldiri Reixac 4, Barcelona, Spain., Jaffrelot M; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.; Department of Digestive Oncology, IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France., Leroy L; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France., Chibon F; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France., Escudie F; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France., Selves J; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France., Hoffmann JS; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France., Guimbaud R; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.; Department of Digestive Oncology, IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France., Lutzmann M; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Institute of Human Genetics, IGH, UMR 9002, Centre National de la Recherche Scientifique, University of Montpellier, 34396Montpellier, France.
Source:	NAR cancer [NAR Cancer] 2023 Mar 11; Vol. 5 (2), pp. zcad011. Date of Electronic Publication: 2023 Mar 11 (Print Publication: 2023).
Publication Type:	Journal Article
Journal Info:	Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: PubMed not MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	2632-8674
DOI:	10.1093/narcan/zcad011