The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.

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Title: The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.
Authors: Labrousse G; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France., Vande Perre P; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France., Parra G; Center for Genomic Analysis, CNAG, Carrer de Baldiri Reixac 4, Barcelona, Spain., Jaffrelot M; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.; Department of Digestive Oncology, IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France., Leroy L; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France., Chibon F; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France., Escudie F; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France., Selves J; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France., Hoffmann JS; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France., Guimbaud R; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.; Department of Digestive Oncology, IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France., Lutzmann M; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Institute of Human Genetics, IGH, UMR 9002, Centre National de la Recherche Scientifique, University of Montpellier, 34396Montpellier, France.
Source: NAR cancer [NAR Cancer] 2023 Mar 11; Vol. 5 (2), pp. zcad011. Date of Electronic Publication: 2023 Mar 11 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101769553 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-8674 (Electronic) Linking ISSN: 26328674 NLM ISO Abbreviation: NAR Cancer Subsets: PubMed not MEDLINE
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  Data: The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.
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  Data: <searchLink fieldCode="AU" term="%22Labrousse+G%22">Labrousse G</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Vande+Perre+P%22">Vande Perre P</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Parra+G%22">Parra G</searchLink>; Center for Genomic Analysis, CNAG, Carrer de Baldiri Reixac 4, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Jaffrelot+M%22">Jaffrelot M</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.; Department of Digestive Oncology, IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Leroy+L%22">Leroy L</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Chibon+F%22">Chibon F</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Escudie+F%22">Escudie F</searchLink>; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Selves+J%22">Selves J</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Hoffmann+JS%22">Hoffmann JS</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Laboratoire d'Excellence Toulouse Cancer (TOUCAN), Laboratoire de Pathologie, Institut Universitaire du Cancer-Toulouse, Oncopole, 1 Avenue Irene-Joliot-Curie, 31059Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Guimbaud+R%22">Guimbaud R</searchLink>; Oncogenetics Department, Institute Claudius Regaud, IUCT-Oncopole, Toulouse, France.; Department of Digestive Oncology, IUCT Rangueil-Larrey, CHU de Toulouse, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Lutzmann+M%22">Lutzmann M</searchLink>; Cancer Research Center of Toulouse, CRCT, 2 Avenue Hubert Curien, 31000Toulouse, France.; Institute of Human Genetics, IGH, UMR 9002, Centre National de la Recherche Scientifique, University of Montpellier, 34396Montpellier, France.
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  Data: <searchLink fieldCode="JN" term="%22101769553%22">NAR cancer</searchLink> [NAR Cancer] 2023 Mar 11; Vol. 5 (2), pp. zcad011. <i>Date of Electronic Publication: </i>2023 Mar 11 (<i>Print Publication: </i>2023).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101769553 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2632-8674 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226328674%22">26328674 </searchLink><i>NLM ISO Abbreviation: </i>NAR Cancer <i>Subsets: </i>PubMed not MEDLINE
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      – TitleFull: The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity.
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