The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity. - Labrousse G; Vande Perre P; Parra G; Jaffrelot M; Leroy L; Chibon F; Escudie F; Selves J; Hoffmann JS; Guimbaud R; Lutzmann M (NAR cancer, 2023)