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Tumor immune microenvironment alterations using induction cetuximab in a phase II trial of deintensified therapy for p16-positive oropharynx cancer.

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Title: Tumor immune microenvironment alterations using induction cetuximab in a phase II trial of deintensified therapy for p16-positive oropharynx cancer.
Authors: Smith JD; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Ludwig ML; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Bhangale AD; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Brummel C; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Swiecicki PL; Division of Hematology & Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Worden FP; Division of Hematology & Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Chinn SB; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Stucken CL; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Rosko AJ; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Prince MEP; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Malloy KM; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Casper KA; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Bradford CR; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Chepeha DB; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Shah J; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Schonewolf CA; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA., McHugh JB; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Nyati MK; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Eisbruch A; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Mierzwa ML; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA., Spector ME; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA., Brenner JC; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Source: Head & neck [Head Neck] 2023 May; Vol. 45 (5), pp. 1281-1287. Date of Electronic Publication: 2023 Mar 18.
Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley And Sons Country of Publication: United States NLM ID: 8902541 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0347 (Electronic) Linking ISSN: 10433074 NLM ISO Abbreviation: Head Neck Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumor immune microenvironment alterations using induction cetuximab in a phase II trial of deintensified therapy for p16-positive oropharynx cancer.
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  Data: <searchLink fieldCode="AU" term="%22Smith+JD%22">Smith JD</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Ludwig+ML%22">Ludwig ML</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Bhangale+AD%22">Bhangale AD</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Brummel+C%22">Brummel C</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Swiecicki+PL%22">Swiecicki PL</searchLink>; Division of Hematology & Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Worden+FP%22">Worden FP</searchLink>; Division of Hematology & Oncology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Chinn+SB%22">Chinn SB</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Stucken+CL%22">Stucken CL</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Rosko+AJ%22">Rosko AJ</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Prince+MEP%22">Prince MEP</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Malloy+KM%22">Malloy KM</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Casper+KA%22">Casper KA</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Bradford+CR%22">Bradford CR</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Chepeha+DB%22">Chepeha DB</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Shah+J%22">Shah J</searchLink>; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Schonewolf+CA%22">Schonewolf CA</searchLink>; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22McHugh+JB%22">McHugh JB</searchLink>; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Nyati+MK%22">Nyati MK</searchLink>; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Eisbruch+A%22">Eisbruch A</searchLink>; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Mierzwa+ML%22">Mierzwa ML</searchLink>; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Spector+ME%22">Spector ME</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Brenner+JC%22">Brenner JC</searchLink>; Department of Otolaryngology - Head & Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA.; Rogel Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, USA.
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  Data: <searchLink fieldCode="JN" term="%228902541%22">Head & neck</searchLink> [Head Neck] 2023 May; Vol. 45 (5), pp. 1281-1287. <i>Date of Electronic Publication: </i>2023 Mar 18.
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