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High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.

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Title: High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.
Authors: Weinschutz Mendes H; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Neelakantan U; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Liu Y; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA., Fitzpatrick SE; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510, USA., Chen T; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Wu W; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA., Pruitt A; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA., Jin DS; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; Department of Neurology, Yale School of Medicine, New Haven, CT 06510, USA., Jamadagni P; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Carlson M; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA., Lacadie CM; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA., Enriquez KD; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Li N; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA; SJTU-Yale Joint Center for Biostatistics and Data Science, Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China., Zhao D; Department of Genetics, Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT 06510, USA., Ijaz S; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Sakai C; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Szi C; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Rooney B; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Ghosh M; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK., Nwabudike I; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA., Gorodezky A; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Chowdhury S; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Zaheer M; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., McLaughlin S; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Fernandez JM; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Wu J; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Eilbott JA; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA., Vander Wyk B; Department of Internal Medicine, Section of Geriatrics, Yale School of Medicine, New Haven, CT 06510, USA., Rihel J; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK., Papademetris X; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA., Wang Z; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA., Hoffman EJ; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: ellen.hoffman@yale.edu.
Source: Cell reports [Cell Rep] 2023 Mar 28; Vol. 42 (3), pp. 112243. Date of Electronic Publication: 2023 Mar 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High-throughput functional analysis of autism genes in zebrafish identifies convergence in dopaminergic and neuroimmune pathways.
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  Data: <searchLink fieldCode="AU" term="%22Weinschutz+Mendes+H%22">Weinschutz Mendes H</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Neelakantan+U%22">Neelakantan U</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Fitzpatrick+SE%22">Fitzpatrick SE</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Wu+W%22">Wu W</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Pruitt+A%22">Pruitt A</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Jin+DS%22">Jin DS</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; Department of Neurology, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Jamadagni+P%22">Jamadagni P</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Carlson+M%22">Carlson M</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Lacadie+CM%22">Lacadie CM</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Enriquez+KD%22">Enriquez KD</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Li+N%22">Li N</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA; SJTU-Yale Joint Center for Biostatistics and Data Science, Department of Bioinformatics and Biostatistics, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.<br /><searchLink fieldCode="AU" term="%22Zhao+D%22">Zhao D</searchLink>; Department of Genetics, Yale Center for Genome Analysis, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Ijaz+S%22">Ijaz S</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Sakai+C%22">Sakai C</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Szi+C%22">Szi C</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Rooney+B%22">Rooney B</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Ghosh+M%22">Ghosh M</searchLink>; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Nwabudike+I%22">Nwabudike I</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06510, USA; MD-PhD Program, Yale School of Medicine, New Haven, CT 06510, USA; Department of Psychiatry, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Gorodezky+A%22">Gorodezky A</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Chowdhury+S%22">Chowdhury S</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Zaheer+M%22">Zaheer M</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22McLaughlin+S%22">McLaughlin S</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Fernandez+JM%22">Fernandez JM</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Eilbott+JA%22">Eilbott JA</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Vander+Wyk+B%22">Vander Wyk B</searchLink>; Department of Internal Medicine, Section of Geriatrics, Yale School of Medicine, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Rihel+J%22">Rihel J</searchLink>; Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.<br /><searchLink fieldCode="AU" term="%22Papademetris+X%22">Papademetris X</searchLink>; Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT 06510, USA; Department of Biomedical Engineering, Yale University, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Department of Biostatistics, Yale School of Public Health, New Haven, CT 06510, USA.<br /><searchLink fieldCode="AU" term="%22Hoffman+EJ%22">Hoffman EJ</searchLink>; Child Study Center, Yale School of Medicine, New Haven, CT 06510, USA; Department of Neuroscience, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: ellen.hoffman@yale.edu.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2023 Mar 28; Vol. 42 (3), pp. 112243. <i>Date of Electronic Publication: </i>2023 Mar 17.
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