Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial.
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| Title: | Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial. |
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| Authors: | Stahl M; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine and.; German Center for Lung Research, Associated Partner Site, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany., Roehmel J; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine and., Eichinger M; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik, and., Doellinger F; Department of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Naehrlich L; Department of Pediatrics, Justus Liebig University Giessen, Giessen, Germany.; Universities of Giessen and Marburg Lung Center, German Center for Lung Research, Giessen, Germany., Kopp MV; Pediatric Respiratory Medicine, Department of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.; Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany., Dittrich AM; Department for Pediatric Pulmonology, Allergology, and Neonatology and.; BREATH, German Center for Lung Research, Hannover Medical School, Hannover, Germany; and., Lee C; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Sommerburg O; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.; Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Department of Pediatrics, Heidelberg University Hospital, Heidelberg, Germany., Tian S; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Xu T; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Wu P; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Joshi A; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Ray P; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Duncan ME; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts., Wielpütz MO; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik, and., Mall MA; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine and.; German Center for Lung Research, Associated Partner Site, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany. |
| Source: | Annals of the American Thoracic Society [Ann Am Thorac Soc] 2023 Aug; Vol. 20 (8), pp. 1144-1155. |
| Publication Type: | Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Thoracic Society Country of Publication: United States NLM ID: 101600811 Publication Model: Print Cited Medium: Internet ISSN: 2325-6621 (Electronic) Linking ISSN: 23256621 NLM ISO Abbreviation: Ann Am Thorac Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 36943405 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Stahl+M%22">Stahl M</searchLink>; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine and.; German Center for Lung Research, Associated Partner Site, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Roehmel+J%22">Roehmel J</searchLink>; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine and.<br /><searchLink fieldCode="AU" term="%22Eichinger+M%22">Eichinger M</searchLink>; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik, and.<br /><searchLink fieldCode="AU" term="%22Doellinger+F%22">Doellinger F</searchLink>; Department of Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Naehrlich+L%22">Naehrlich L</searchLink>; Department of Pediatrics, Justus Liebig University Giessen, Giessen, Germany.; Universities of Giessen and Marburg Lung Center, German Center for Lung Research, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Kopp+MV%22">Kopp MV</searchLink>; Pediatric Respiratory Medicine, Department of Pediatrics, Inselspital, University of Bern, Bern, Switzerland.; Airway Research Center North, German Center for Lung Research, Grosshansdorf, Germany.<br /><searchLink fieldCode="AU" term="%22Dittrich+AM%22">Dittrich AM</searchLink>; Department for Pediatric Pulmonology, Allergology, and Neonatology and.; BREATH, German Center for Lung Research, Hannover Medical School, Hannover, Germany; and.<br /><searchLink fieldCode="AU" term="%22Lee+C%22">Lee C</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Sommerburg+O%22">Sommerburg O</searchLink>; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.; Division of Pediatric Pulmonology and Allergy and Cystic Fibrosis Center, Department of Pediatrics, Heidelberg University Hospital, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Tian+S%22">Tian S</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Xu+T%22">Xu T</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Wu+P%22">Wu P</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Joshi+A%22">Joshi A</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Ray+P%22">Ray P</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Duncan+ME%22">Duncan ME</searchLink>; Vertex Pharmaceuticals Incorporated, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Wielpütz+MO%22">Wielpütz MO</searchLink>; Translational Lung Research Center Heidelberg, German Center for Lung Research, Heidelberg, Germany.; Department of Diagnostic and Interventional Radiology.; Department of Diagnostic and Interventional Radiology with Nuclear Medicine, Thoraxklinik, and.<br /><searchLink fieldCode="AU" term="%22Mall+MA%22">Mall MA</searchLink>; Department of Pediatric Respiratory Medicine, Immunology, and Critical Care Medicine and.; German Center for Lung Research, Associated Partner Site, Berlin, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101600811%22">Annals of the American Thoracic Society</searchLink> [Ann Am Thorac Soc] 2023 Aug; Vol. 20 (8), pp. 1144-1155. – Name: TypePub Label: Publication Type Group: TypPub Data: Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Thoracic+Society%22">American Thoracic Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101600811 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2325-6621 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223256621%22">23256621 </searchLink><i>NLM ISO Abbreviation: </i>Ann Am Thorac Soc <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=36943405 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1513/AnnalsATS.202208-684OC Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1144 Titles: – TitleFull: Effects of Lumacaftor/Ivacaftor on Cystic Fibrosis Disease Progression in Children 2 through 5 Years of Age Homozygous for F508del-CFTR: A Phase 2 Placebo-controlled Clinical Trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Stahl M – PersonEntity: Name: NameFull: Roehmel J – PersonEntity: Name: NameFull: Eichinger M – PersonEntity: Name: NameFull: Doellinger F – PersonEntity: Name: NameFull: Naehrlich L – PersonEntity: Name: NameFull: Kopp MV – PersonEntity: Name: NameFull: Dittrich AM – PersonEntity: Name: NameFull: Lee C – PersonEntity: Name: NameFull: Sommerburg O – PersonEntity: Name: NameFull: Tian S – PersonEntity: Name: NameFull: Xu T – PersonEntity: Name: NameFull: Wu P – PersonEntity: Name: NameFull: Joshi A – PersonEntity: Name: NameFull: Ray P – PersonEntity: Name: NameFull: Duncan ME – PersonEntity: Name: NameFull: Wielpütz MO – PersonEntity: Name: NameFull: Mall MA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2023 Aug Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 2325-6621 Numbering: – Type: volume Value: 20 – Type: issue Value: 8 Titles: – TitleFull: Annals of the American Thoracic Society Type: main |
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