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The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.

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Title: The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.
Authors: Shen Q; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516., Kumari S; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702., Xu C; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716., Jang S; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.; Department of Medicine, Harvard Medical School, Boston, MA 02115., Shi J; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232., Burdick RC; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702., Levintov L; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716., Xiong Q; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516., Wu C; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511., Devarkar SC; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511., Tian T; Nanobiology Institute, Yale University, West Haven, CT 06516., Tripler TN; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511., Hu Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511., Yuan S; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511., Temple J; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511., Feng Q; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516., Lusk CP; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520., Aiken C; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232., Engelman AN; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.; Department of Medicine, Harvard Medical School, Boston, MA 02115., Perilla JR; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716., Pathak VK; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702., Lin C; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516.; Department of Biomedical Engineering, Yale University, New Haven, CT 06511., Xiong Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Mar 28; Vol. 120 (13), pp. e2202815120. Date of Electronic Publication: 2023 Mar 21.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores.
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  Data: <searchLink fieldCode="AU" term="%22Shen+Q%22">Shen Q</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516.<br /><searchLink fieldCode="AU" term="%22Kumari+S%22">Kumari S</searchLink>; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716.<br /><searchLink fieldCode="AU" term="%22Jang+S%22">Jang S</searchLink>; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.; Department of Medicine, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Shi+J%22">Shi J</searchLink>; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.<br /><searchLink fieldCode="AU" term="%22Burdick+RC%22">Burdick RC</searchLink>; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702.<br /><searchLink fieldCode="AU" term="%22Levintov+L%22">Levintov L</searchLink>; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716.<br /><searchLink fieldCode="AU" term="%22Xiong+Q%22">Xiong Q</searchLink>; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516.<br /><searchLink fieldCode="AU" term="%22Wu+C%22">Wu C</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Devarkar+SC%22">Devarkar SC</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Tian+T%22">Tian T</searchLink>; Nanobiology Institute, Yale University, West Haven, CT 06516.<br /><searchLink fieldCode="AU" term="%22Tripler+TN%22">Tripler TN</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Hu+Y%22">Hu Y</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Yuan+S%22">Yuan S</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Temple+J%22">Temple J</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Feng+Q%22">Feng Q</searchLink>; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516.<br /><searchLink fieldCode="AU" term="%22Lusk+CP%22">Lusk CP</searchLink>; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.<br /><searchLink fieldCode="AU" term="%22Aiken+C%22">Aiken C</searchLink>; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232.<br /><searchLink fieldCode="AU" term="%22Engelman+AN%22">Engelman AN</searchLink>; Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215.; Department of Medicine, Harvard Medical School, Boston, MA 02115.<br /><searchLink fieldCode="AU" term="%22Perilla+JR%22">Perilla JR</searchLink>; Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716.<br /><searchLink fieldCode="AU" term="%22Pathak+VK%22">Pathak VK</searchLink>; HIV Dynamics and Replication Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick, MD 21702.<br /><searchLink fieldCode="AU" term="%22Lin+C%22">Lin C</searchLink>; Department of Cell Biology, Yale School of Medicine, New Haven, CT 06520.; Nanobiology Institute, Yale University, West Haven, CT 06516.; Department of Biomedical Engineering, Yale University, New Haven, CT 06511.<br /><searchLink fieldCode="AU" term="%22Xiong+Y%22">Xiong Y</searchLink>; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06511.
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