Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study.

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Title: Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study.
Authors: Mangino JE; Division of Infection Diseases, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States., Firstenberg MS; William Novick Global Cardiac Alliance. Aurora, Colorado, United States., Milewski RKC; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, United States., Rhys-Williams W; Destiny Pharma, Brighton, United Kingdom., Lees JP; Destiny Pharma, Brighton, United Kingdom., Dane A; Danestat Consulting Ltd, Macclesfield, United Kingdom., Love WG; Destiny Pharma, Brighton, United Kingdom., Gonzalez Moreno J; Destiny Pharma, Brighton, United Kingdom.
Source: Infection control and hospital epidemiology [Infect Control Hosp Epidemiol] 2023 Jul; Vol. 44 (7), pp. 1171-1173. Date of Electronic Publication: 2023 Mar 23.
Publication Type: Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cambridge University Press Country of Publication: United States NLM ID: 8804099 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-6834 (Electronic) Linking ISSN: 0899823X NLM ISO Abbreviation: Infect Control Hosp Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study.
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  Data: <searchLink fieldCode="AU" term="%22Mangino+JE%22">Mangino JE</searchLink>; Division of Infection Diseases, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States.<br /><searchLink fieldCode="AU" term="%22Firstenberg+MS%22">Firstenberg MS</searchLink>; William Novick Global Cardiac Alliance. Aurora, Colorado, United States.<br /><searchLink fieldCode="AU" term="%22Milewski+RKC%22">Milewski RKC</searchLink>; Department of Surgery, Yale School of Medicine, New Haven, Connecticut, United States.<br /><searchLink fieldCode="AU" term="%22Rhys-Williams+W%22">Rhys-Williams W</searchLink>; Destiny Pharma, Brighton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Lees+JP%22">Lees JP</searchLink>; Destiny Pharma, Brighton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dane+A%22">Dane A</searchLink>; Danestat Consulting Ltd, Macclesfield, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Love+WG%22">Love WG</searchLink>; Destiny Pharma, Brighton, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gonzalez+Moreno+J%22">Gonzalez Moreno J</searchLink>; Destiny Pharma, Brighton, United Kingdom.
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  Data: <searchLink fieldCode="JN" term="%228804099%22">Infection control and hospital epidemiology</searchLink> [Infect Control Hosp Epidemiol] 2023 Jul; Vol. 44 (7), pp. 1171-1173. <i>Date of Electronic Publication: </i>2023 Mar 23.
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  Data: Randomized Controlled Trial; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
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        Value: 10.1017/ice.2023.17
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        Text: English
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      – TitleFull: Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study.
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              Text: 2023 Jul
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              Y: 2023
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