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mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.

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Title: mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.
Authors: Moreews M; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Mathieu AL; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Pouxvielh K; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Reuschlé Q; INSERM UMR-S1109, Department of Clinical Immunology and Internal Medicine, National Reference Center for Systemic Autoimmune Diseases, Tertiary Center for Primary Immunodeficiency, Faculty of Pharmacy, Université de Strasbourg, Strasbourg, France., Drouillard A; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Dessay P; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Meignien M; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, Lyon, France., Zhang J; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Fallone L; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Rousseaux N; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Ainouze M; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Rey A; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Omarjee O; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Decembre E; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Lenief V; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Djebali S; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Thaunat O; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.; Department of Transplantation, Nephrology and Clinical Immunology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.; Lyon-Est Medical Faculty, Claude Bernard University (Lyon 1), Lyon, France., Dreux M; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Genestier L; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Defrance T; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Soulas-Sprauel P; INSERM UMR-S1109, Department of Clinical Immunology and Internal Medicine, National Reference Center for Systemic Autoimmune Diseases, Tertiary Center for Primary Immunodeficiency, Faculty of Pharmacy, Université de Strasbourg, Strasbourg, France., Marçais A; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Walzer T; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France., Belot A; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, Lyon, France.
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2023 May 01; Vol. 210 (9), pp. 1209-1221.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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Items – Name: Title
  Label: Title
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  Data: mTOR Activation Underlies Enhanced B Cell Proliferation and Autoimmunity in PrkcdG510S/G510S Mice.
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  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Moreews+M%22">Moreews M</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Mathieu+AL%22">Mathieu AL</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Pouxvielh+K%22">Pouxvielh K</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Reuschlé+Q%22">Reuschlé Q</searchLink>; INSERM UMR-S1109, Department of Clinical Immunology and Internal Medicine, National Reference Center for Systemic Autoimmune Diseases, Tertiary Center for Primary Immunodeficiency, Faculty of Pharmacy, Université de Strasbourg, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Drouillard+A%22">Drouillard A</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Dessay+P%22">Dessay P</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Meignien+M%22">Meignien M</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Fallone+L%22">Fallone L</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Rousseaux+N%22">Rousseaux N</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Ainouze+M%22">Ainouze M</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Rey+A%22">Rey A</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Omarjee+O%22">Omarjee O</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Decembre+E%22">Decembre E</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Lenief+V%22">Lenief V</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Djebali+S%22">Djebali S</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Thaunat+O%22">Thaunat O</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.; Department of Transplantation, Nephrology and Clinical Immunology, Edouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France.; Lyon-Est Medical Faculty, Claude Bernard University (Lyon 1), Lyon, France.<br /><searchLink fieldCode="AU" term="%22Dreux+M%22">Dreux M</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Genestier+L%22">Genestier L</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Defrance+T%22">Defrance T</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Soulas-Sprauel+P%22">Soulas-Sprauel P</searchLink>; INSERM UMR-S1109, Department of Clinical Immunology and Internal Medicine, National Reference Center for Systemic Autoimmune Diseases, Tertiary Center for Primary Immunodeficiency, Faculty of Pharmacy, Université de Strasbourg, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Marçais+A%22">Marçais A</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Walzer+T%22">Walzer T</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Belot+A%22">Belot A</searchLink>; CIRI, Centre International de Recherche en Infectiologie, (Team LYACTS), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, Lyon, France.; Hospices Civils de Lyon, Edouard Herriot Hospital, Immunology Laboratory, Lyon, France.
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  Data: <searchLink fieldCode="JN" term="%222985117R%22">Journal of immunology (Baltimore, Md. : 1950)</searchLink> [J Immunol] 2023 May 01; Vol. 210 (9), pp. 1209-1221.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>2985117R <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1550-6606 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200221767%22">00221767 </searchLink><i>NLM ISO Abbreviation: </i>J Immunol <i>Subsets: </i>MEDLINE
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