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Structural insights into the human niacin receptor HCA2-Gi signalling complex.

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Title: Structural insights into the human niacin receptor HCA2-Gi signalling complex.
Authors: Yang Y; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Kang HJ; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA.; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea., Gao R; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Wang J; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Han GW; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA, 90089, USA., DiBerto JF; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA., Wu L; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Tong J; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Qu L; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Wu Y; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Pileski R; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA.; Department of Obstetrics and Gynecology, Duke University, Durham, NC, USA., Li X; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Zhang XC; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China., Zhao S; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Kenakin T; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA., Wang Q; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China., Stevens RC; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China., Peng W; Innovation Center for Pathogen Research, Guangzhou Laboratory, Guangzhou, 510320, China. peng_wei@gzlab.ac.cn., Roth BL; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA. bryan_roth@med.unc.edu., Rao Z; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. raozh@tsinghua.edu.cn.; University of Chinese Academy of Sciences, Beijing, 100049, China. raozh@tsinghua.edu.cn., Liu ZJ; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China. liuzhj@shanghaitech.edu.cn.
Source: Nature communications [Nat Commun] 2023 Mar 27; Vol. 14 (1), pp. 1692. Date of Electronic Publication: 2023 Mar 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Structural insights into the human niacin receptor HCA2-G<subscript>i</subscript> signalling complex.
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  Data: <searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Kang+HJ%22">Kang HJ</searchLink>; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA.; Department of Biological Sciences, Sungkyunkwan University, Suwon, South Korea.<br /><searchLink fieldCode="AU" term="%22Gao+R%22">Gao R</searchLink>; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Han+GW%22">Han GW</searchLink>; Departments of Biological Sciences and Chemistry, Bridge Institute, University of Southern California, Los Angeles, CA, 90089, USA.<br /><searchLink fieldCode="AU" term="%22DiBerto+JF%22">DiBerto JF</searchLink>; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA.<br /><searchLink fieldCode="AU" term="%22Wu+L%22">Wu L</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Tong+J%22">Tong J</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Qu+L%22">Qu L</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Pileski+R%22">Pileski R</searchLink>; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA.; Department of Obstetrics and Gynecology, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XC%22">Zhang XC</searchLink>; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.; University of Chinese Academy of Sciences, Beijing, 100049, China.<br /><searchLink fieldCode="AU" term="%22Zhao+S%22">Zhao S</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Kenakin+T%22">Kenakin T</searchLink>; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.<br /><searchLink fieldCode="AU" term="%22Stevens+RC%22">Stevens RC</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China.<br /><searchLink fieldCode="AU" term="%22Peng+W%22">Peng W</searchLink>; Innovation Center for Pathogen Research, Guangzhou Laboratory, Guangzhou, 510320, China. peng_wei@gzlab.ac.cn.<br /><searchLink fieldCode="AU" term="%22Roth+BL%22">Roth BL</searchLink>; Department of Pharmacology, and NIMH Psychoactive Drug Screening Program University of North Carolina Chapel Hill Medical School, Chapel Hill, NC, 27514, USA. bryan_roth@med.unc.edu.<br /><searchLink fieldCode="AU" term="%22Rao+Z%22">Rao Z</searchLink>; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China. raozh@tsinghua.edu.cn.; University of Chinese Academy of Sciences, Beijing, 100049, China. raozh@tsinghua.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+ZJ%22">Liu ZJ</searchLink>; iHuman Institute, ShanghaiTech University, Shanghai, 201210, China. liuzhj@shanghaitech.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2023 Mar 27; Vol. 14 (1), pp. 1692. <i>Date of Electronic Publication: </i>2023 Mar 27.
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