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Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation.

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Title: Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation.
Authors: Gopal K; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Karwi QG; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Tabatabaei Dakhili SA; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Wagg CS; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Zhang L; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Sun Q; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Saed CT; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Panidarapu S; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada., Perfetti R; Applied Therapeutics, New York, NY, USA., Ramasamy R; Diabetes Research Program, New York University Grossman Medical Center, New York, NY, USA., Ussher JR; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada., Lopaschuk GD; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada. gary.lopaschuk@ualberta.ca.
Source: Cardiovascular diabetology [Cardiovasc Diabetol] 2023 Mar 28; Vol. 22 (1), pp. 73. Date of Electronic Publication: 2023 Mar 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147637 Publication Model: Electronic Cited Medium: Internet ISSN: 1475-2840 (Electronic) Linking ISSN: 14752840 NLM ISO Abbreviation: Cardiovasc Diabetol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation.
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  Data: <searchLink fieldCode="AU" term="%22Gopal+K%22">Gopal K</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Karwi+QG%22">Karwi QG</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Tabatabaei+Dakhili+SA%22">Tabatabaei Dakhili SA</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Wagg+CS%22">Wagg CS</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+L%22">Zhang L</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Sun+Q%22">Sun Q</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Saed+CT%22">Saed CT</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Panidarapu+S%22">Panidarapu S</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Perfetti+R%22">Perfetti R</searchLink>; Applied Therapeutics, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ramasamy+R%22">Ramasamy R</searchLink>; Diabetes Research Program, New York University Grossman Medical Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ussher+JR%22">Ussher JR</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada.; Faculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, AB, Canada.; Alberta Diabetes Institute, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Lopaschuk+GD%22">Lopaschuk GD</searchLink>; Cardiovascular Research Institute, University of Alberta, Edmonton, AB, Canada. gary.lopaschuk@ualberta.ca.
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  Data: <searchLink fieldCode="JN" term="%22101147637%22">Cardiovascular diabetology</searchLink> [Cardiovasc Diabetol] 2023 Mar 28; Vol. 22 (1), pp. 73. <i>Date of Electronic Publication: </i>2023 Mar 28.
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