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Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance.

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Title: Diosmin nanocrystal gel alleviates imiquimod-induced psoriasis in rats via modulating TLR7,8/NF-κB/micro RNA-31, AKT/mTOR/P70S6K milieu, and Tregs/Th17 balance.
Authors: Shahine Y; Department of Microbiology & Immunology, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt., El-Aal SAA; Department of Pharmacy, Kut University College, Al Kut, Wasit, 52001, Iraq., Reda AM; Department of Pharmacy, Kut University College, Al Kut, Wasit, 52001, Iraq.; Department of Biochemistry, Faculty of Pharmacy, Egyptian Russian University, Badr City, Cairo, Egypt., Sheta E; Department of Pathology, Faculty of Medicine, Alexandria University, Alexandria, Egypt., Atia NM; Department of Pharmaceutics, Faculty of Pharmacy, Pharos University in Alexandria, Alexandria, Egypt., Abdallah OY; Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt., Ibrahim SSA; Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Pharos University in Alexandria (PUA), Canal El- Mahmoudia Street, Smouha, Alexandria, Egypt. Sherihan.abdelhamid@pua.edu.eg.
Source: Inflammopharmacology [Inflammopharmacology] 2023 Jun; Vol. 31 (3), pp. 1341-1359. Date of Electronic Publication: 2023 Apr 03.
Publication Type: Journal Article
Journal Info: Publisher: Birkhäuser Country of Publication: Switzerland NLM ID: 9112626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1568-5608 (Electronic) Linking ISSN: 09254692 NLM ISO Abbreviation: Inflammopharmacology Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1568-5608
DOI:10.1007/s10787-023-01198-w