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Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease.

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Title: Longitudinal head-to-head comparison of 11C-PiB and 18F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease.
Authors: Chen CD; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA.; Washington University School of Medicine, 660 South Euclid, Campus Box 8225, St. Louis, MO, 63110, USA., McCullough A; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Gordon B; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Joseph-Mathurin N; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Flores S; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., McKay NS; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Hobbs DA; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Hornbeck R; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA., Fagan AM; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Cruchaga C; Department of Psychiatry, Washington University in St. Louis, St. Louis, MO, USA., Goate AM; Department of Genetics and Genomic Sciences, Ichan School of Medicine at Mount Sinai, New York, NY, USA., Perrin RJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA., Wang G; Department of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., Li Y; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Shi X; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Xiong C; Department of Biostatistics, Washington University in St. Louis, St. Louis, MO, USA., Pontecorvo MJ; Avid Radiopharmaceuticals, Philadelphia, PA, USA.; Eli Lilly and Company, Indianapolis, IN, USA., Klein G; F. Hoffmann-La Roche Ltd., Basel, Switzerland., Su Y; Banner Alzheimer's Institute, Banner Health, Phoenix, AZ, USA.; Arizona Alzheimer's Consortium, Phoenix, AZ, USA., Klunk WE; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA., Jack C; Department of Radiology, Mayo Clinic, Rochester, MN, USA., Koeppe R; Department of Radiology, University of Michigan, Ann Arbor, MI, USA., Snider BJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Berman SB; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA., Roberson ED; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Brosch J; Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA., Surti G; Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA., Jiménez-Velázquez IZ; Department of Medicine, University of Puerto Rico School of Medicine, San Juan, PR, USA., Galasko D; Department of Neurology, University of California San Diego, San Diego, CA, USA., Honig LS; Department of Neurology, Columbia University, New York, NY, USA., Brooks WS; Prince of Wales Medical Research Institute, University of New South Wales, Sydney, NSW, Australia., Clarnette R; Department of Internal Medicine, University of Western Australia, Crawley, WA, Australia., Wallon D; Department of Neurology and CNR-MAJ, Normandie Univ, UNIROUEN, INSERM U1245, CHU Rouen, F-76000, Rouen, France., Dubois B; Sorbonne Université, AP-HP, GRC No. 21, APM, Hôpital de La Pitié-Salpêtrière, Paris, France.; Institut du Cerveau Et de La Moelle Épinière, INSERM U1127, CNRS UMR 7225, Paris, France.; Institut de La Mémoire Et de La Maladie d'Alzheimer, Département de Neurologie, Hôpital de La Pitié-Salpêtrière, Paris, France., Pariente J; Department of Neurology, Hôpital Pierre-Paul Riquet, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.; Toulouse NeuroImaging Centre, Université de Toulouse, INSERM, UPS, Toulouse, France., Pasquier F; Univ. Lille, INSERM, CHU Lille, 59000, Lille, France.; CNR-MAJ, Labex DISTALZ, LiCEND, 59000, Lille, France., Sanchez-Valle R; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital ClínicInstitut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Fundació Clínic Per a La Recerca Biomèdica, University of Barcelona, Barcelona, Spain., Shcherbinin S; Eli Lilly and Company, Indianapolis, IN, USA., Higgins I; Eli Lilly and Company, Indianapolis, IN, USA., Tunali I; Eli Lilly and Company, Indianapolis, IN, USA., Masters CL; The Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia., van Dyck CH; Yale School of Medicine, New Haven, CT, USA., Masellis M; Sunnybrook Research Institute, Toronto, ON, Canada., Hsiung R; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada., Gauthier S; Douglas Mental Health University Institute, Montreal, QC, Canada., Salloway S; Alpert Medical School of Brown University, Providence, RI, USA., Clifford DB; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Mills S; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Supnet-Bell C; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., McDade E; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Bateman RJ; Department of Neurology, Washington University in St. Louis, St. Louis, MO, USA., Benzinger TLS; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, MO, USA. benzingert@wustl.edu.
Corporate Authors: DIAN-TU Study Team
Source: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2023 Jul; Vol. 50 (9), pp. 2669-2682. Date of Electronic Publication: 2023 Apr 05.
Publication Type: Clinical Trial, Phase III; Clinical Trial, Phase II; Journal Article
Journal Info: Publisher: Springer-Verlag Berlin Country of Publication: Germany NLM ID: 101140988 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1619-7089 (Electronic) Linking ISSN: 16197070 NLM ISO Abbreviation: Eur J Nucl Med Mol Imaging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Longitudinal head-to-head comparison of <superscript>11</superscript>C-PiB and <superscript>18</superscript>F-florbetapir PET in a Phase 2/3 clinical trial of anti-amyloid-β monoclonal antibodies in dominantly inherited Alzheimer's disease.
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          Identifiers:
            – Type: issn-electronic
              Value: 1619-7089
          Numbering:
            – Type: volume
              Value: 50
            – Type: issue
              Value: 9
          Titles:
            – TitleFull: European journal of nuclear medicine and molecular imaging
              Type: main
ResultId 1