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High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long-COVID-19 patients.

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Title: High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long-COVID-19 patients.
Authors: Gomes SMR; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil., Brito ACS; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil., Manfro WFP; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil., Ribeiro-Alves M; Laboratory of Clinical Research on STD/AIDS, National Institute of Infectology Evandro Chagas, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, RJ, Brazil., Ribeiro RSA; Laboratory of Immunopathology, Department of General Pathology and Laboratories, FCM, UERJ, Rio de Janeiro, RJ, Brazil., da Cal MS; Pulmonary and Tisiology Department, Pedro Ernesto University Hospital (HUPE), Policlínica Piquet Carneiro (PPC)/UERJ, Rio de Janeiro, RJ, Brazil., Lisboa VDC; Laboratory of Immunopathology, Department of General Pathology and Laboratories, FCM, UERJ, Rio de Janeiro, RJ, Brazil., Abreu DPB; Chemical Engineering Program, Cell Culture Engineering Lab (COPPE), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil., Castilho LDR; Chemical Engineering Program, Cell Culture Engineering Lab (COPPE), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil., Porto LCMS; Histocompatibility and Cryopreservation Laboratory, Department of Histology and Embryology Institute of Biology Roberto Alcantara Gomes, UERJ, Rio de Janeiro, RJ, Brazil., Mafort TT; Pulmonary and Tisiology Department, Pedro Ernesto University Hospital (HUPE), Policlínica Piquet Carneiro (PPC)/UERJ, Rio de Janeiro, RJ, Brazil., Lopes AJ; Pulmonary and Tisiology Department, Pedro Ernesto University Hospital (HUPE), Policlínica Piquet Carneiro (PPC)/UERJ, Rio de Janeiro, RJ, Brazil., da Silva SAG; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil., Dutra PML; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil., Rodrigues LS; Laboratory of Immunopathology, Department of General Pathology and Laboratories, FCM, UERJ, Rio de Janeiro, RJ, Brazil.
Source: PloS one [PLoS One] 2023 Apr 05; Vol. 18 (4), pp. e0283983. Date of Electronic Publication: 2023 Apr 05 (Print Publication: 2023).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: High levels of pro-inflammatory SARS-CoV-2-specific biomarkers revealed by in vitro whole blood cytokine release assay (CRA) in recovered and long-COVID-19 patients.
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  Data: <searchLink fieldCode="AU" term="%22Gomes+SMR%22">Gomes SMR</searchLink>; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Brito+ACS%22">Brito ACS</searchLink>; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Manfro+WFP%22">Manfro WFP</searchLink>; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro-Alves+M%22">Ribeiro-Alves M</searchLink>; Laboratory of Clinical Research on STD/AIDS, National Institute of Infectology Evandro Chagas, Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Ribeiro+RSA%22">Ribeiro RSA</searchLink>; Laboratory of Immunopathology, Department of General Pathology and Laboratories, FCM, UERJ, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Cal+MS%22">da Cal MS</searchLink>; Pulmonary and Tisiology Department, Pedro Ernesto University Hospital (HUPE), Policlínica Piquet Carneiro (PPC)/UERJ, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Lisboa+VDC%22">Lisboa VDC</searchLink>; Laboratory of Immunopathology, Department of General Pathology and Laboratories, FCM, UERJ, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Abreu+DPB%22">Abreu DPB</searchLink>; Chemical Engineering Program, Cell Culture Engineering Lab (COPPE), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Castilho+LDR%22">Castilho LDR</searchLink>; Chemical Engineering Program, Cell Culture Engineering Lab (COPPE), Federal University of Rio de Janeiro (UFRJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Porto+LCMS%22">Porto LCMS</searchLink>; Histocompatibility and Cryopreservation Laboratory, Department of Histology and Embryology Institute of Biology Roberto Alcantara Gomes, UERJ, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Mafort+TT%22">Mafort TT</searchLink>; Pulmonary and Tisiology Department, Pedro Ernesto University Hospital (HUPE), Policlínica Piquet Carneiro (PPC)/UERJ, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Lopes+AJ%22">Lopes AJ</searchLink>; Pulmonary and Tisiology Department, Pedro Ernesto University Hospital (HUPE), Policlínica Piquet Carneiro (PPC)/UERJ, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+SAG%22">da Silva SAG</searchLink>; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Dutra+PML%22">Dutra PML</searchLink>; Department of Microbiology, Parasitology and Immunology, Medical Science Faculty (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+LS%22">Rodrigues LS</searchLink>; Laboratory of Immunopathology, Department of General Pathology and Laboratories, FCM, UERJ, Rio de Janeiro, RJ, Brazil.
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  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2023 Apr 05; Vol. 18 (4), pp. e0283983. <i>Date of Electronic Publication: </i>2023 Apr 05 (<i>Print Publication: </i>2023).
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