Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses.
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| Title: | Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses. |
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| Authors: | Shrock EL; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Program in Biological and Biomedical Sciences, Harvard University, Boston, MA 02115, USA., Timms RT; Cambridge Institute of Therapeutic Immunology and Infectious Disease, Jeffrey Cheah Biomedical Centre, Cambridge Biomedical Campus, University of Cambridge, Cambridge, UK., Kula T; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA.; Program in Biological and Biomedical Sciences, Harvard University, Boston, MA 02115, USA., Mena EL; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA., West AP Jr; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Guo R; Division of Infectious Disease, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA., Lee IH; Center for Systems Biology, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA., Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., McKay LGA; National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston University, Boston, MA 02118, USA., Bi C; Division of Allergy and Immunology, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA 02115, USA., Leng Y; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA., Fujimura E; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA., Horns F; Department of Bioengineering, Department of Applied Physics, Chan Zuckerberg Biohub and Stanford University, Stanford, CA 94305, USA., Li M; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA., Wesemann DR; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Division of Allergy and Immunology, Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Massachusetts Consortium on Pathogen Readiness, Boston, MA 02115, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, 02139 USA., Griffiths A; National Emerging Infectious Diseases Laboratories, Boston University School of Medicine, Boston University, Boston, MA 02118, USA., Gewurz BE; Division of Infectious Disease, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.; Graduate Program in Virology, Division of Medical Sciences, Harvard Medical School, Boston, MA 02115, USA., Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA., Elledge SJ; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.; Division of Genetics, Department of Medicine, Howard Hughes Medical Institute, Brigham and Women's Hospital, Boston, MA 02115, USA. |
| Source: | Science (New York, N.Y.) [Science] 2023 Apr 07; Vol. 380 (6640), pp. eadc9498. Date of Electronic Publication: 2023 Apr 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1095-9203 |
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| DOI: | 10.1126/science.adc9498 |
