Radiation treatment of benign tumors in NF2-related-schwannomatosis: A national study of 266 irradiated patients showing a significant increase in malignancy/malignant progression.

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Title: Radiation treatment of benign tumors in NF2-related-schwannomatosis: A national study of 266 irradiated patients showing a significant increase in malignancy/malignant progression.
Authors: Evans DG; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK., Halliday D; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust., Obholzer R; Department of ENT, and Neurology, London, UK., Afridi S; Guy's and St Thomas' NHS Trust, London, UK., Forde C; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK., Rutherford SA; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Hammerbeck-Ward C; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Lloyd SK; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Freeman SM; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Pathmanaban ON; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.; Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK., Thomas OM; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Laitt RD; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Stivaros S; Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, M13 9PL, UK.; Academic Unit of Paediatric Radiology, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK., Kilday JP; Children's Brain Tumour Research Network (CBTRN), Royal Manchester Children's Hospital, Manchester, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK., Vassallo G; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK., McBain C; The Christie NHS Foundation Trust, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK., Lavin T; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK., Paterson C; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK., Whitfield G; Children's Brain Tumour Research Network (CBTRN), Royal Manchester Children's Hospital, Manchester, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.; The Christie NHS Foundation Trust, Manchester, UK., McCabe MG; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.; The Christie NHS Foundation Trust, Manchester, UK., Axon PR; Department of Otolaryngology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., Halliday J; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust., Mackeith S; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust., Parry A; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust., Harkness EF; Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, M13 9PL, UK.; Prevent Breast Cancer Centre, Wythenshawe Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK., Buttimore J; Department of Otolaryngology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK., King AT; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK.; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.
Corporate Authors: English Specialist NF2 Research Group
Source: Neuro-oncology advances [Neurooncol Adv] 2023 Mar 11; Vol. 5 (1), pp. vdad025. Date of Electronic Publication: 2023 Mar 11 (Print Publication: 2023).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755003 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-2498 (Electronic) Linking ISSN: 26322498 NLM ISO Abbreviation: Neurooncol Adv Subsets: PubMed not MEDLINE
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  Data: Radiation treatment of benign tumors in NF2-related-schwannomatosis: A national study of 266 irradiated patients showing a significant increase in malignancy/malignant progression.
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  Data: <searchLink fieldCode="AU" term="%22Evans+DG%22">Evans DG</searchLink>; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Halliday+D%22">Halliday D</searchLink>; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust.<br /><searchLink fieldCode="AU" term="%22Obholzer+R%22">Obholzer R</searchLink>; Department of ENT, and Neurology, London, UK.<br /><searchLink fieldCode="AU" term="%22Afridi+S%22">Afridi S</searchLink>; Guy's and St Thomas' NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Forde+C%22">Forde C</searchLink>; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Rutherford+SA%22">Rutherford SA</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Hammerbeck-Ward+C%22">Hammerbeck-Ward C</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Lloyd+SK%22">Lloyd SK</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Freeman+SM%22">Freeman SM</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Pathmanaban+ON%22">Pathmanaban ON</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.; Division of Neuroscience and Experimental Psychology, Faculty of Biology, Medicine and Health, University of Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+OM%22">Thomas OM</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Laitt+RD%22">Laitt RD</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Stivaros+S%22">Stivaros S</searchLink>; Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, M13 9PL, UK.; Academic Unit of Paediatric Radiology, Royal Manchester Children's Hospital, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Kilday+JP%22">Kilday JP</searchLink>; Children's Brain Tumour Research Network (CBTRN), Royal Manchester Children's Hospital, Manchester, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Vassallo+G%22">Vassallo G</searchLink>; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22McBain+C%22">McBain C</searchLink>; The Christie NHS Foundation Trust, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Lavin+T%22">Lavin T</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Paterson+C%22">Paterson C</searchLink>; Division of Evolution and Genomic Medicine, Manchester Centre for Genomic Medicine, Manchester Academic Health Science Centre, University of Manchester, St Mary's Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Whitfield+G%22">Whitfield G</searchLink>; Children's Brain Tumour Research Network (CBTRN), Royal Manchester Children's Hospital, Manchester, UK.; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.; The Christie NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22McCabe+MG%22">McCabe MG</searchLink>; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.; The Christie NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Axon+PR%22">Axon PR</searchLink>; Department of Otolaryngology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Halliday+J%22">Halliday J</searchLink>; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust.<br /><searchLink fieldCode="AU" term="%22Mackeith+S%22">Mackeith S</searchLink>; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust.<br /><searchLink fieldCode="AU" term="%22Parry+A%22">Parry A</searchLink>; Departments of Genomic Medicine, Neurology, Neurosurgery, ENT, Oxford University Hospitals NHS Foundation Trust.<br /><searchLink fieldCode="AU" term="%22Harkness+EF%22">Harkness EF</searchLink>; Division of Informatics, Imaging and Data Sciences, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester Academic Health Science Centre, Oxford Road, Manchester, M13 9PL, UK.; Prevent Breast Cancer Centre, Wythenshawe Hospital, Manchester Universities NHS Foundation Trust, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Buttimore+J%22">Buttimore J</searchLink>; Department of Otolaryngology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22King+AT%22">King AT</searchLink>; Departments of Neurosurgery, Otolaryngology, Neuroradiology, and Neurology, Manchester Centre for Clinical Neurosciences Salford Royal Hospital, Northern Care Alliance NHS Foundation Trust, Manchester, UK.; Geoffrey Jefferson Brain Research Centre, Manchester Academic Health Science Centre, Northern Care Alliance NHS Foundation Trust, University of Manchester, UK.; Division of Cardiovascular Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK.
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