Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment.
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| Title: | Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment. |
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| Authors: | Ertveldt T; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Krasniqi A; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium., Ceuppens H; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Puttemans J; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium., Dekempeneer Y; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium., Jonghe K; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium., Mey W; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Lecocq Q; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Vlaeminck Y; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Awad RM; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Goyvaerts C; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium., Veirman K; Department of Hematology and Immunology, Myeloma Center Brussels, Vrije Universiteit Brussel, Brussels, Belgium., Morgenstern A; European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Karlsruhe Institut, Germany; and., Bruchertseifer F; European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Karlsruhe Institut, Germany; and., Keyaerts M; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.; Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium., Devoogdt N; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium., D'Huyvetter M; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium., Breckpot K; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium; Karine.Breckpot@vub.be. |
| Source: | Journal of nuclear medicine : official publication, Society of Nuclear Medicine [J Nucl Med] 2023 May; Vol. 64 (5), pp. 751-758. Date of Electronic Publication: 2023 Apr 13. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Society of Nuclear Medicine Country of Publication: United States NLM ID: 0217410 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-5667 (Electronic) Linking ISSN: 01615505 NLM ISO Abbreviation: J Nucl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37055223 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Targeted α-Therapy Using <superscript>225</superscript>Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ertveldt+T%22">Ertveldt T</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Krasniqi+A%22">Krasniqi A</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Ceuppens+H%22">Ceuppens H</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Puttemans+J%22">Puttemans J</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Dekempeneer+Y%22">Dekempeneer Y</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Jonghe+K%22">Jonghe K</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Mey+W%22">Mey W</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Lecocq+Q%22">Lecocq Q</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Vlaeminck+Y%22">Vlaeminck Y</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Awad+RM%22">Awad RM</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Goyvaerts+C%22">Goyvaerts C</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Veirman+K%22">Veirman K</searchLink>; Department of Hematology and Immunology, Myeloma Center Brussels, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Morgenstern+A%22">Morgenstern A</searchLink>; European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Karlsruhe Institut, Germany; and.<br /><searchLink fieldCode="AU" term="%22Bruchertseifer+F%22">Bruchertseifer F</searchLink>; European Commission, Joint Research Centre, Directorate for Nuclear Safety and Security, Karlsruhe Institut, Germany; and.<br /><searchLink fieldCode="AU" term="%22Keyaerts+M%22">Keyaerts M</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.; Department of Nuclear Medicine, UZ Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Devoogdt+N%22">Devoogdt N</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22D'Huyvetter+M%22">D'Huyvetter M</searchLink>; Department of Medical Imaging, In Vivo Cellular and Molecular Imaging Laboratory, Vrije Universiteit Brussel, Brussels, Belgium.<br /><searchLink fieldCode="AU" term="%22Breckpot+K%22">Breckpot K</searchLink>; Department of Biomedical Sciences, Laboratory for Molecular and Cellular Therapy, Vrije Universiteit Brussel, Brussels, Belgium; Karine.Breckpot@vub.be. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220217410%22">Journal of nuclear medicine : official publication, Society of Nuclear Medicine</searchLink> [J Nucl Med] 2023 May; Vol. 64 (5), pp. 751-758. <i>Date of Electronic Publication: </i>2023 Apr 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Society+of+Nuclear+Medicine%22">Society of Nuclear Medicine </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0217410 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1535-5667 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201615505%22">01615505 </searchLink><i>NLM ISO Abbreviation: </i>J Nucl Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37055223 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.2967/jnumed.122.264752 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 751 Titles: – TitleFull: Targeted α-Therapy Using 225Ac Radiolabeled Single-Domain Antibodies Induces Antigen-Specific Immune Responses and Instills Immunomodulation Both Systemically and at the Tumor Microenvironment. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ertveldt T – PersonEntity: Name: NameFull: Krasniqi A – PersonEntity: Name: NameFull: Ceuppens H – PersonEntity: Name: NameFull: Puttemans J – PersonEntity: Name: NameFull: Dekempeneer Y – PersonEntity: Name: NameFull: Jonghe K – PersonEntity: Name: NameFull: Mey W – PersonEntity: Name: NameFull: Lecocq Q – PersonEntity: Name: NameFull: Vlaeminck Y – PersonEntity: Name: NameFull: Awad RM – PersonEntity: Name: NameFull: Goyvaerts C – PersonEntity: Name: NameFull: Veirman K – PersonEntity: Name: NameFull: Morgenstern A – PersonEntity: Name: NameFull: Bruchertseifer F – PersonEntity: Name: NameFull: Keyaerts M – PersonEntity: Name: NameFull: Devoogdt N – PersonEntity: Name: NameFull: D'Huyvetter M – PersonEntity: Name: NameFull: Breckpot K IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: 2023 May Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1535-5667 Numbering: – Type: volume Value: 64 – Type: issue Value: 5 Titles: – TitleFull: Journal of nuclear medicine : official publication, Society of Nuclear Medicine Type: main |
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