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Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.

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Title: Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.
Authors: Aaghaz S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India., Digwal CS; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India., Neshat N; School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi 110062, India., Maurya IK; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India., Kumar V; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India., Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India., Jain R; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India. Electronic address: rahuljain@niper.ac.in., Kamal A; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India; Birla Institute of Technology & Science (BITS), Pilani Hyderabad Campus, Hyderabad, Telangana, 500078, India. Electronic address: ahmedkamal@iict.res.in.
Source: Bioorganic chemistry [Bioorg Chem] 2023 Jul; Vol. 136, pp. 106538. Date of Electronic Publication: 2023 Apr 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.
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  Data: <searchLink fieldCode="AU" term="%22Aaghaz+S%22">Aaghaz S</searchLink>; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India.<br /><searchLink fieldCode="AU" term="%22Digwal+CS%22">Digwal CS</searchLink>; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India.<br /><searchLink fieldCode="AU" term="%22Neshat+N%22">Neshat N</searchLink>; School of Pharmaceutical Education and Research (SPER), Jamia Hamdard, New Delhi 110062, India.<br /><searchLink fieldCode="AU" term="%22Maurya+IK%22">Maurya IK</searchLink>; Center of Infectious Diseases, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India.<br /><searchLink fieldCode="AU" term="%22Kumar+V%22">Kumar V</searchLink>; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India.<br /><searchLink fieldCode="AU" term="%22Tikoo+K%22">Tikoo K</searchLink>; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research, S.A.S. Nagar, Punjab 160062, India.<br /><searchLink fieldCode="AU" term="%22Jain+R%22">Jain R</searchLink>; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, S.A.S Nagar, Punjab 160062, India. Electronic address: rahuljain@niper.ac.in.<br /><searchLink fieldCode="AU" term="%22Kamal+A%22">Kamal A</searchLink>; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Balanagar, Hyderabad 500037, India; Birla Institute of Technology & Science (BITS), Pilani Hyderabad Campus, Hyderabad, Telangana, 500078, India. Electronic address: ahmedkamal@iict.res.in.
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  Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2023 Jul; Vol. 136, pp. 106538. <i>Date of Electronic Publication: </i>2023 Apr 13.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bioorg.2023.106538
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      – Code: eng
        Text: English
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      – TitleFull: Synthesis, biological evaluation and mechanistic studies of 4-(1,3-thiazol-2-yl)morpholine-benzimidazole hybrids as a new structural class of antimicrobials.
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            – D: 01
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              Text: 2023 Jul
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              Y: 2023
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