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Utility of CYP2D6 copy number variants as prognostic biomarker in localized anal squamous cell carcinoma.

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Title: Utility of CYP2D6 copy number variants as prognostic biomarker in localized anal squamous cell carcinoma.
Authors: Trilla-Fuertes L; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain., Gámez-Pozo A; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain.; Biomedica Molecular Medicine SL, Madrid, Spain., Nogué M; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital de Granollers, Barcelona, Spain., Busquier I; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Provincial de Castellón, Castellón, Spain., Arias F; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Radiotherapy Oncology Service, Complejo Hospitalario de Navarra, Navarra, Spain., López-Campos F; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Radiotherapy Oncology Service, Hospital Ramón y Cajal, Madrid, Spain., Fernández-Montes A; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Complejo Hospitalario Universitario de Ourense, Ourense, Spain., Ruiz A; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, Madrid, Spain., Velázquez C; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Miguel Servet, Zaragoza, Spain., Martín-Bravo C; Medical Oncology Service, Hospital Costa del Sol, Málaga, Spain., Pérez-Ruiz E; Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga, Hospitales Universitarios Regional y Virgen de la Victoria, Málaga, Spain., Asensio E; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital General Universitario de Elche, Elche, Spain., Hernández-Yagüe X; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Instituto Catalán de Oncología-Girona, Girona, Spain., Rodrigues A; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario de Salamanca, Salamanca, Spain., Ghanem I; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario La Paz, Madrid, Spain., López-Vacas R; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain., Hafez A; Biotechvana SL, Parque Científico de Madrid, Madrid, Spain., Arias P; Pharmacogenetics Lab, Institute of Medical and Molecular Genetics-INGEMM, La Paz University Hospital-IdiPAZ, Autonomous University of Madrid, Madrid, Spain., Dapía I; Pharmacogenetics Lab, Institute of Medical and Molecular Genetics-INGEMM, La Paz University Hospital-IdiPAZ, Autonomous University of Madrid, Madrid, Spain., Solís M; Bioinformatics Unit, Institute of Medical and Molecular Genetics-INGEMM, La Paz University Hospital-IdiPAZ, Madrid, Spain., Dittmann A; Functional Genomics Center Zurich, University of Zurich/ETH Zurich, Zurich, Switzerland., Ramos R; Genomics Unit, Parque Científico de Madrid, Madrid, Spain., Llorens C; Biotechvana SL, Parque Científico de Madrid, Madrid, Spain., Maurel J; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Department, Hospital Clínic of Barcelona, Translational Genomics and Targeted Therapeutics in Solid Tumors Group, IDIBAPS, University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain., Campos-Barros Á; Institute of Medical and Molecular Genetics, IdiPAZ, Hospital Universitario La Paz/CIBERER Unit 753, ISCIII, Madrid, Spain., Fresno Vara JÁ; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain.; Biomedica Molecular Medicine SL, Madrid, Spain.; Biomedical Research Networking Center on Oncology-CIBERONC, ISCIII, Madrid, Spain., Feliu J; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario La Paz, Madrid, Spain.; Biomedical Research Networking Center on Oncology-CIBERONC, ISCIII, Madrid, Spain.; Cátedra UAM-Amgen, Universidad Autónoma de Madrid, Madrid, Spain.
Source: Cancer [Cancer] 2023 Aug 15; Vol. 129 (16), pp. 2581-2592. Date of Electronic Publication: 2023 Apr 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0374236 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0142 (Electronic) Linking ISSN: 0008543X NLM ISO Abbreviation: Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Utility of CYP2D6 copy number variants as prognostic biomarker in localized anal squamous cell carcinoma.
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  Data: <searchLink fieldCode="AU" term="%22Trilla-Fuertes+L%22">Trilla-Fuertes L</searchLink>; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gámez-Pozo+A%22">Gámez-Pozo A</searchLink>; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain.; Biomedica Molecular Medicine SL, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Nogué+M%22">Nogué M</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital de Granollers, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Busquier+I%22">Busquier I</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Provincial de Castellón, Castellón, Spain.<br /><searchLink fieldCode="AU" term="%22Arias+F%22">Arias F</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Radiotherapy Oncology Service, Complejo Hospitalario de Navarra, Navarra, Spain.<br /><searchLink fieldCode="AU" term="%22López-Campos+F%22">López-Campos F</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Radiotherapy Oncology Service, Hospital Ramón y Cajal, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández-Montes+A%22">Fernández-Montes A</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Complejo Hospitalario Universitario de Ourense, Ourense, Spain.<br /><searchLink fieldCode="AU" term="%22Ruiz+A%22">Ruiz A</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario Puerta de Hierro Majadahonda, IDIPHISA, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Velázquez+C%22">Velázquez C</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Miguel Servet, Zaragoza, Spain.<br /><searchLink fieldCode="AU" term="%22Martín-Bravo+C%22">Martín-Bravo C</searchLink>; Medical Oncology Service, Hospital Costa del Sol, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Ruiz+E%22">Pérez-Ruiz E</searchLink>; Unidad de Gestión Clínica Intercentros de Oncología Médica, Hospitales Universitarios Regional y Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga, Hospitales Universitarios Regional y Virgen de la Victoria, Málaga, Spain.<br /><searchLink fieldCode="AU" term="%22Asensio+E%22">Asensio E</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital General Universitario de Elche, Elche, Spain.<br /><searchLink fieldCode="AU" term="%22Hernández-Yagüe+X%22">Hernández-Yagüe X</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Instituto Catalán de Oncología-Girona, Girona, Spain.<br /><searchLink fieldCode="AU" term="%22Rodrigues+A%22">Rodrigues A</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario de Salamanca, Salamanca, Spain.<br /><searchLink fieldCode="AU" term="%22Ghanem+I%22">Ghanem I</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario La Paz, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22López-Vacas+R%22">López-Vacas R</searchLink>; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Hafez+A%22">Hafez A</searchLink>; Biotechvana SL, Parque Científico de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Arias+P%22">Arias P</searchLink>; Pharmacogenetics Lab, Institute of Medical and Molecular Genetics-INGEMM, La Paz University Hospital-IdiPAZ, Autonomous University of Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Dapía+I%22">Dapía I</searchLink>; Pharmacogenetics Lab, Institute of Medical and Molecular Genetics-INGEMM, La Paz University Hospital-IdiPAZ, Autonomous University of Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Solís+M%22">Solís M</searchLink>; Bioinformatics Unit, Institute of Medical and Molecular Genetics-INGEMM, La Paz University Hospital-IdiPAZ, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Dittmann+A%22">Dittmann A</searchLink>; Functional Genomics Center Zurich, University of Zurich/ETH Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Ramos+R%22">Ramos R</searchLink>; Genomics Unit, Parque Científico de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Llorens+C%22">Llorens C</searchLink>; Biotechvana SL, Parque Científico de Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Maurel+J%22">Maurel J</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Department, Hospital Clínic of Barcelona, Translational Genomics and Targeted Therapeutics in Solid Tumors Group, IDIBAPS, University of Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Campos-Barros+Á%22">Campos-Barros Á</searchLink>; Institute of Medical and Molecular Genetics, IdiPAZ, Hospital Universitario La Paz/CIBERER Unit 753, ISCIII, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fresno+Vara+JÁ%22">Fresno Vara JÁ</searchLink>; Molecular Oncology Lab, Hospital Universitario La Paz-IdiPAZ, Madrid, Spain.; Biomedica Molecular Medicine SL, Madrid, Spain.; Biomedical Research Networking Center on Oncology-CIBERONC, ISCIII, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Feliu+J%22">Feliu J</searchLink>; Spanish Multidisciplinary Group of Digestive Cancer, Barcelona, Spain.; Medical Oncology Service, Hospital Universitario La Paz, Madrid, Spain.; Biomedical Research Networking Center on Oncology-CIBERONC, ISCIII, Madrid, Spain.; Cátedra UAM-Amgen, Universidad Autónoma de Madrid, Madrid, Spain.
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  Data: <searchLink fieldCode="JN" term="%220374236%22">Cancer</searchLink> [Cancer] 2023 Aug 15; Vol. 129 (16), pp. 2581-2592. <i>Date of Electronic Publication: </i>2023 Apr 25.
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