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Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial.

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Title: Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial.
Authors: Arjona-Sánchez A; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Espinosa-Redondo E; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Gutiérrez-Calvo A; Unit of Peritoneal Oncologic Surgery, Surgery Department, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain., Segura-Sampedro JJ; Unit of Oncologic and Pancreatic Surgery, Hospital Son Espases, Palma de Mallorca, Spain., Pérez-Viejo E; Unit of Oncologic Surgery, University Hospital of Fuenlabrada, Madrid, Spain., Concepción-Martín V; Unit of Peritoneal Oncologic Surgery and Colorectal Surgery, Hospital University Nuestra Señora de la Candelaria, Tenerife, Spain., Sánchez-García S; Unit of Surgery, University Hospital Ciudad Real, Ciudad Real, Spain., García-Fadrique A; Department of Surgery, Instituto Valenciano de Oncología, Valencia, Spain., Prieto-Nieto I; Unit of Oncologic Surgery, La Paz University Hospital, Madrid, Spain., Barrios-Sanchez P; Unit of Surgery, Consorci Sanitari Integral, Hospital de Sant Joan Despí Moises Broggi, Barcelona, Spain., Torres-Melero J; Unit of Surgery, Hospital de Torrecárdenas, Almería, Spain., Ramírez Faraco M; Unit of Oncologic Surgery, University General Hospital Reina Sofia, Murcia, Spain., Prada-Villaverde A; Unit of Surgery, Infanta Cristina University Hospital, Badajoz, Spain., Carrasco-Campos J; Unit of Surgery, Hospital Regional University of Málaga, Málaga, Spain., Artiles-Armas M; Department of General and Digestive Surgery, University Hospital of Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Canary Islands, Spain., Villarejo-Campos P; Unit of Oncologic Surgery, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Ortega-Pérez G; MD Anderson Cancer Center, Madrid, Spain., Boldo-Roda E; Unit of Surgery, Hospital Provincial de Castellón, Castellón, Spain., Sánchez-Hidalgo JM; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Casado-Adam A; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Rodríguez-Ortiz L; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Aranda E; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain.; Unit of Medical Oncology, University Hospital Reina Sofia, Córdoba, Spain., Cano-Osuna MT; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain.; Unit of Medical Oncology, University Hospital Reina Sofia, Córdoba, Spain., Díaz-López C; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Romero-Ruiz A; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Briceño-Delgado J; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain., Rufián-Peña S; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain.
Corporate Authors: Grupo Español de Carcinomatosis Peritoneal
Source: JAMA surgery [JAMA Surg] 2023 Jul 01; Vol. 158 (7), pp. 683-691.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589553 Publication Model: Print Cited Medium: Internet ISSN: 2168-6262 (Electronic) Linking ISSN: 21686254 NLM ISO Abbreviation: JAMA Surg Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and Safety of Intraoperative Hyperthermic Intraperitoneal Chemotherapy for Locally Advanced Colon Cancer: A Phase 3 Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Arjona-Sánchez+A%22">Arjona-Sánchez A</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Espinosa-Redondo+E%22">Espinosa-Redondo E</searchLink>; Unit of Oncologic and Pancreatic Surgery, University Hospital Reina Sofia, Córdoba, Spain.; Maimónides Biomedical Research Institute of Córdoba, University Hospital Reina Sofia, University of Córdoba, Córdoba, Spain.<br /><searchLink fieldCode="AU" term="%22Gutiérrez-Calvo+A%22">Gutiérrez-Calvo A</searchLink>; Unit of Peritoneal Oncologic Surgery, Surgery Department, Hospital Príncipe de Asturias, Alcalá de Henares, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Segura-Sampedro+JJ%22">Segura-Sampedro JJ</searchLink>; Unit of Oncologic and Pancreatic Surgery, Hospital Son Espases, Palma de Mallorca, Spain.<br /><searchLink fieldCode="AU" term="%22Pérez-Viejo+E%22">Pérez-Viejo E</searchLink>; Unit of Oncologic Surgery, University Hospital of Fuenlabrada, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Concepción-Martín+V%22">Concepción-Martín V</searchLink>; Unit of Peritoneal Oncologic Surgery and Colorectal Surgery, Hospital University Nuestra Señora de la Candelaria, Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Sánchez-García+S%22">Sánchez-García S</searchLink>; Unit of Surgery, University Hospital Ciudad Real, Ciudad Real, Spain.<br /><searchLink fieldCode="AU" term="%22García-Fadrique+A%22">García-Fadrique A</searchLink>; Department of Surgery, Instituto Valenciano de Oncología, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Prieto-Nieto+I%22">Prieto-Nieto I</searchLink>; Unit of Oncologic Surgery, La Paz University Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Barrios-Sanchez+P%22">Barrios-Sanchez P</searchLink>; Unit of Surgery, Consorci Sanitari Integral, Hospital de Sant Joan Despí Moises Broggi, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Torres-Melero+J%22">Torres-Melero J</searchLink>; 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