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Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.

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Title: Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.
Authors: Kum DB; Aligos Belgium BV, Leuven, Belgium.; Aligos Therapeutics Inc., South San Francisco, California, USA., Vanrusselt H; Aligos Belgium BV, Leuven, Belgium., Acosta Sanchez A; Novalix, Leuven, Belgium., Taverniti V; Strasbourg University, Inserm, Institute for Research on Viral and Hepatic Diseases, UMR S1110, Strasbourg, France., Verrier ER; Strasbourg University, Inserm, Institute for Research on Viral and Hepatic Diseases, UMR S1110, Strasbourg, France., Baumert TF; Strasbourg University, Inserm, Institute for Research on Viral and Hepatic Diseases, UMR S1110, Strasbourg, France.; Hepato-digestive Division, IHU Strasbourg, Strasbourg University Hospitals, Strasbourg, France., Liu C; Aligos Therapeutics Inc., South San Francisco, California, USA., Deval J; Aligos Therapeutics Inc., South San Francisco, California, USA., Corthout N; VIB Bio-imaging Core, Leuven, Belgium., Munck S; VIB Bio-imaging Core, Leuven, Belgium., Beigelman L; Aligos Therapeutics Inc., South San Francisco, California, USA., Blatt LM; Aligos Therapeutics Inc., South San Francisco, California, USA., Symons JA; Aligos Therapeutics Inc., South San Francisco, California, USA., Raboisson P; Aligos Belgium BV, Leuven, Belgium., Jekle A; Aligos Therapeutics Inc., South San Francisco, California, USA., Vendeville S; Aligos Belgium BV, Leuven, Belgium., Debing Y; Aligos Belgium BV, Leuven, Belgium.
Source: Hepatology (Baltimore, Md.) [Hepatology] 2023 Oct 01; Vol. 78 (4), pp. 1252-1265. Date of Electronic Publication: 2023 Apr 28.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Class A capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation.
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  Data: <searchLink fieldCode="AU" term="%22Kum+DB%22">Kum DB</searchLink>; Aligos Belgium BV, Leuven, Belgium.; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Vanrusselt+H%22">Vanrusselt H</searchLink>; Aligos Belgium BV, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Acosta+Sanchez+A%22">Acosta Sanchez A</searchLink>; Novalix, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Taverniti+V%22">Taverniti V</searchLink>; Strasbourg University, Inserm, Institute for Research on Viral and Hepatic Diseases, UMR S1110, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Verrier+ER%22">Verrier ER</searchLink>; Strasbourg University, Inserm, Institute for Research on Viral and Hepatic Diseases, UMR S1110, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Baumert+TF%22">Baumert TF</searchLink>; Strasbourg University, Inserm, Institute for Research on Viral and Hepatic Diseases, UMR S1110, Strasbourg, France.; Hepato-digestive Division, IHU Strasbourg, Strasbourg University Hospitals, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Deval+J%22">Deval J</searchLink>; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Corthout+N%22">Corthout N</searchLink>; VIB Bio-imaging Core, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Munck+S%22">Munck S</searchLink>; VIB Bio-imaging Core, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Beigelman+L%22">Beigelman L</searchLink>; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Blatt+LM%22">Blatt LM</searchLink>; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Symons+JA%22">Symons JA</searchLink>; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Raboisson+P%22">Raboisson P</searchLink>; Aligos Belgium BV, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Jekle+A%22">Jekle A</searchLink>; Aligos Therapeutics Inc., South San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Vendeville+S%22">Vendeville S</searchLink>; Aligos Belgium BV, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Debing+Y%22">Debing Y</searchLink>; Aligos Belgium BV, Leuven, Belgium.
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  Data: <searchLink fieldCode="JN" term="%228302946%22">Hepatology (Baltimore, Md.)</searchLink> [Hepatology] 2023 Oct 01; Vol. 78 (4), pp. 1252-1265. <i>Date of Electronic Publication: </i>2023 Apr 28.
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  Data: Journal Article; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Inc%22">Wolters Kluwer Health, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8302946 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-3350 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202709139%22">02709139 </searchLink><i>NLM ISO Abbreviation: </i>Hepatology <i>Subsets: </i>MEDLINE
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              Text: 2023 Oct 01
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