An innovative phase 2 proof-of-concept trial design to evaluate SAR445088, a monoclonal antibody targeting complement C1s in chronic inflammatory demyelinating polyneuropathy.
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| Title: | An innovative phase 2 proof-of-concept trial design to evaluate SAR445088, a monoclonal antibody targeting complement C1s in chronic inflammatory demyelinating polyneuropathy. |
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| Authors: | Querol L; Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.; Centro para la Investigación Biomédica en Red en Enfermedades Raras (CIBERER), Madrid, Spain., Lewis RA; Cedars Sinai Medical Center, Los Angeles, California, USA., Hartung HP; Department of Neurology, Faculty of Medicine, Heinrich Heine University, Düsseldorf, Germany.; Brain and Mind Center, University of Sydney, Sydney, New South Wales, Australia.; Department of Neurology, Medical University of Vienna, Vienna, Austria.; Department of Neurology, Palacky University Olomouc, Olomouc, Czech Republic., Van Doorn PA; Erasmus MC, University Medical Center, Rotterdam, The Netherlands., Wallstroem E; Neurology Development, Sanofi R&D, Cambridge, Massachusetts, USA., Luo X; Biostatistics and Programming, Sanofi R&D, Bridgewater, New Jersey, USA., Alonso-Alonso M; Neurology Development, Sanofi R&D, Cambridge, Massachusetts, USA., Atassi N; Neurology Development, Sanofi R&D, Cambridge, Massachusetts, USA., Hughes RAC; UCL Queen Square Institute of Neurology, University College London, London, UK. |
| Source: | Journal of the peripheral nervous system : JPNS [J Peripher Nerv Syst] 2023 Jun; Vol. 28 (2), pp. 276-285. Date of Electronic Publication: 2023 May 31. |
| Publication Type: | Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 9704532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-8027 (Electronic) Linking ISSN: 10859489 NLM ISO Abbreviation: J Peripher Nerv Syst Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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