Riluzole in Spinal Cord Injury Study (RISCIS)-Pharmacokinetic (PK) Sub-Study: An Analysis of Pharmacokinetics, Pharmacodynamics, and Impact on Axonal Degradation of Riluzole in Patients With Traumatic Cervical Spinal Cord Injury Enrolled in the RISCIS Phase III Randomized Controlled Trial.
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| Title: | Riluzole in Spinal Cord Injury Study (RISCIS)-Pharmacokinetic (PK) Sub-Study: An Analysis of Pharmacokinetics, Pharmacodynamics, and Impact on Axonal Degradation of Riluzole in Patients With Traumatic Cervical Spinal Cord Injury Enrolled in the RISCIS Phase III Randomized Controlled Trial. |
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| Authors: | Chow DS; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas, USA., Nguyen A; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas, USA.; Janssen Pharmaceutical Companies of Johnson & Johnson, Philadelphia, Pennsylvania, USA., Park J; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas, USA., Wu L; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas, USA.; AbbVie Pharmaceuticals, Chicago, Illinois, USA., Toups EG; Department of Neurosurgery, Houston Methodist Research Institute, Houston, Texas, USA., Harrop JS; Department of Neurosurgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA., Guest JD; Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA., Schmitt KM; Department of Neurosurgery, Health Science Center, University of Texas, Houston, Texas, USA., Aarabi B; Department of Neurosurgery, University of Maryland, Baltimore, Maryland, USA., Fehlings MG; Division of Neurosurgery and Spine Program, Toronto Western Hospital, University of Toronto, Ontario, Canada., Boakye M; Department of Neurosurgery, University of Louisville, Louisville, Kentucky, USA., Grossman RG; Department of Neurosurgery, Houston Methodist Research Institute, Houston, Texas, USA. |
| Source: | Journal of neurotrauma [J Neurotrauma] 2023 Sep; Vol. 40 (17-18), pp. 1889-1906. |
| Publication Type: | Randomized Controlled Trial; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Mary Ann Liebert Country of Publication: United States NLM ID: 8811626 Publication Model: Print Cited Medium: Internet ISSN: 1557-9042 (Electronic) Linking ISSN: 08977151 NLM ISO Abbreviation: J Neurotrauma Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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