Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at hMC1R and hMC4R.
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| Title: | Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH |
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| Authors: | Zhou Y; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States., Mowlazadeh Haghighi S; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States., Sawyer JR; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States., Hruby VJ; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States., Cai M; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2023 May 25; Vol. 66 (10), pp. 6715-6724. Date of Electronic Publication: 2023 May 03. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37133411 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH<subscript>2</subscript> Lead to Potent and Selective Agonists at hMC1R and hMC4R. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhou+Y%22">Zhou Y</searchLink>; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States.<br /><searchLink fieldCode="AU" term="%22Mowlazadeh+Haghighi+S%22">Mowlazadeh Haghighi S</searchLink>; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States.<br /><searchLink fieldCode="AU" term="%22Sawyer+JR%22">Sawyer JR</searchLink>; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States.<br /><searchLink fieldCode="AU" term="%22Hruby+VJ%22">Hruby VJ</searchLink>; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States.<br /><searchLink fieldCode="AU" term="%22Cai+M%22">Cai M</searchLink>; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, Arizona 85721, United States. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2023 May 25; Vol. 66 (10), pp. 6715-6724. <i>Date of Electronic Publication: </i>2023 May 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=37133411 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.jmedchem.2c01794 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 6715 Titles: – TitleFull: Ψ and χ Angle Constrains at the C-Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His-d-Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at hMC1R and hMC4R. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhou Y – PersonEntity: Name: NameFull: Mowlazadeh Haghighi S – PersonEntity: Name: NameFull: Sawyer JR – PersonEntity: Name: NameFull: Hruby VJ – PersonEntity: Name: NameFull: Cai M IsPartOfRelationships: – BibEntity: Dates: – D: 25 M: 05 Text: 2023 May 25 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 1520-4804 Numbering: – Type: volume Value: 66 – Type: issue Value: 10 Titles: – TitleFull: Journal of medicinal chemistry Type: main |
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