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In vivo activity of the dual PI3Kδ and PI3Kγ inhibitor duvelisib against pediatric acute lymphoblastic leukemia xenografts.

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Title: In vivo activity of the dual PI3Kδ and PI3Kγ inhibitor duvelisib against pediatric acute lymphoblastic leukemia xenografts.
Authors: Randall J; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia., Evans K; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia., Watts B; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia., Smith CM; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia., Hughes K; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia., Earley EJ; RTI International, Research Triangle Park, North Carolina, USA., Erickson SW; RTI International, Research Triangle Park, North Carolina, USA., Pachter JA; Verastem Oncology, Inc., Needham, Massachusetts, USA., Teicher BA; National Cancer Institute, Bethesda, Maryland, USA., Smith MA; National Cancer Institute, Bethesda, Maryland, USA., Lock RB; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.
Source: Pediatric blood & cancer [Pediatr Blood Cancer] 2023 Aug; Vol. 70 (8), pp. e30398. Date of Electronic Publication: 2023 May 04.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: John Wiley Country of Publication: United States NLM ID: 101186624 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-5017 (Electronic) Linking ISSN: 15455009 NLM ISO Abbreviation: Pediatr Blood Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In vivo activity of the dual PI3Kδ and PI3Kγ inhibitor duvelisib against pediatric acute lymphoblastic leukemia xenografts.
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  Data: <searchLink fieldCode="AU" term="%22Randall+J%22">Randall J</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Evans+K%22">Evans K</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Watts+B%22">Watts B</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Smith+CM%22">Smith CM</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Hughes+K%22">Hughes K</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Earley+EJ%22">Earley EJ</searchLink>; RTI International, Research Triangle Park, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Erickson+SW%22">Erickson SW</searchLink>; RTI International, Research Triangle Park, North Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Pachter+JA%22">Pachter JA</searchLink>; Verastem Oncology, Inc., Needham, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Teicher+BA%22">Teicher BA</searchLink>; National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Smith+MA%22">Smith MA</searchLink>; National Cancer Institute, Bethesda, Maryland, USA.<br /><searchLink fieldCode="AU" term="%22Lock+RB%22">Lock RB</searchLink>; Children's Cancer Institute, Lowy Cancer Research Centre, School of Clinical Medicine, UNSW Medicine & Health, Centre for Childhood Cancer Research, UNSW Sydney, Sydney, New South Wales, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101186624%22">Pediatric blood & cancer</searchLink> [Pediatr Blood Cancer] 2023 Aug; Vol. 70 (8), pp. e30398. <i>Date of Electronic Publication: </i>2023 May 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley%22">John Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101186624 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1545-5017 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215455009%22">15455009 </searchLink><i>NLM ISO Abbreviation: </i>Pediatr Blood Cancer <i>Subsets: </i>MEDLINE
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              Text: 2023 Aug
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