Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity.
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| Title: | Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity. |
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| Authors: | Wang C; Discovery Chemistry, Merck & Co., Inc., West Point, PA 19486, USA., Adam GC; Screening and Protein Science, Merck & Co., Inc., West Point, PA 19486, USA., Burlein C; Pharmacology, Merck & Co., Inc., West Point, PA 19486, USA., Carroll S; Pharmacology, Merck & Co., Inc., West Point, PA 19486, USA., Dankulich W; Discovery Chemistry, Merck & Co., Inc., West Point, PA 19486, USA., Diamond T; Infectious Disease Biology Discovery, Merck & Co., Inc., West Point, PA 19486, USA., Grobler J; Infectious Disease Biology Discovery, Merck & Co., Inc., West Point, PA 19486, USA., Heath J; Infectious Disease Biology Discovery, Merck & Co., Inc., West Point, PA 19486, USA., Johnson A; Discovery Chemistry, Merck & Co., Inc., West Point, PA 19486, USA., Klein D; Computational and Structural Chemistry, Merck & Co., Inc., West Point, PA 19486, USA., Krosky D; Pharmacology, Merck & Co., Inc., West Point, PA 19486, USA., Narayan K; Pharmacology, Merck & Co., Inc., West Point, PA 19486, USA., Ou Y; Pharmacology, Merck & Co., Inc., West Point, PA 19486, USA., Sanders J; Computational and Structural Chemistry, Merck & Co., Inc., West Point, PA 19486, USA., Sharma S; Screening and Protein Science, Merck & Co., Inc., West Point, PA 19486, USA., Xu M; Pharmacology, Merck & Co., Inc., West Point, PA 19486, USA., Converso A; Discovery Chemistry, Merck & Co., Inc., West Point, PA 19486, USA. Electronic address: antonella_converso@merck.com. |
| Source: | Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2023 Jun 01; Vol. 89, pp. 129303. Date of Electronic Publication: 2023 May 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9107377 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3405 (Electronic) Linking ISSN: 0960894X NLM ISO Abbreviation: Bioorg Med Chem Lett Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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