Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.

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Title: Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.
Authors: Burger MC; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Forster MT; Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany., Romanski A; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Straßheimer F; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Macas J; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Zeiner PS; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Steidl E; Institute of Neuroradiology, Goethe University Hospital, Frankfurt, Germany., Herkt S; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Weber KJ; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center (UCT), Goethe University Hospital, Frankfurt, Germany., Schupp J; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Lun JH; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Strecker MI; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Wlotzka K; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Cakmak P; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Opitz C; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany., George R; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Department of Radiotherapy and Oncology, Goethe University Hospital, Frankfurt, Germany., Mildenberger IC; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany., Nowakowska P; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Zhang C; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Röder J; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany., Müller E; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Ihrig K; University Cancer Center (UCT), Goethe University Hospital, Frankfurt, Germany., Langen KJ; Research Center Jülich, Institute of Neuroscience and Medicine, Jülich, Germany.; Department of Nuclear Medicine, University Hospital Aachen, Aachen, Germany., Rieger MA; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt, Germany., Herrmann E; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt, Germany., Bonig H; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany., Harter PN; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Reiss Y; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Hattingen E; Institute of Neuroradiology, Goethe University Hospital, Frankfurt, Germany., Rödel F; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Department of Radiotherapy and Oncology, Goethe University Hospital, Frankfurt, Germany., Plate KH; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany., Tonn T; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany., Senft C; Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany., Steinbach JP; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany., Wels WS; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
Source: Neuro-oncology [Neuro Oncol] 2023 Nov 02; Vol. 25 (11), pp. 2058-2071.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 100887420 Publication Model: Print Cited Medium: Internet ISSN: 1523-5866 (Electronic) Linking ISSN: 15228517 NLM ISO Abbreviation: Neuro Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Intracranial injection of natural killer cells engineered with a HER2-targeted chimeric antigen receptor in patients with recurrent glioblastoma.
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  Data: <searchLink fieldCode="AU" term="%22Burger+MC%22">Burger MC</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Forster+MT%22">Forster MT</searchLink>; Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Romanski+A%22">Romanski A</searchLink>; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Straßheimer+F%22">Straßheimer F</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Macas+J%22">Macas J</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Zeiner+PS%22">Zeiner PS</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Steidl+E%22">Steidl E</searchLink>; Institute of Neuroradiology, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Herkt+S%22">Herkt S</searchLink>; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Weber+KJ%22">Weber KJ</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; University Cancer Center (UCT), Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Schupp+J%22">Schupp J</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lun+JH%22">Lun JH</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Strecker+MI%22">Strecker MI</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Wlotzka+K%22">Wlotzka K</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Cakmak+P%22">Cakmak P</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Opitz+C%22">Opitz C</searchLink>; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22George+R%22">George R</searchLink>; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Department of Radiotherapy and Oncology, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Mildenberger+IC%22">Mildenberger IC</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Nowakowska+P%22">Nowakowska P</searchLink>; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Röder+J%22">Röder J</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Müller+E%22">Müller E</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Ihrig+K%22">Ihrig K</searchLink>; University Cancer Center (UCT), Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Langen+KJ%22">Langen KJ</searchLink>; Research Center Jülich, Institute of Neuroscience and Medicine, Jülich, Germany.; Department of Nuclear Medicine, University Hospital Aachen, Aachen, Germany.<br /><searchLink fieldCode="AU" term="%22Rieger+MA%22">Rieger MA</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Herrmann+E%22">Herrmann E</searchLink>; Institute for Biostatistics and Mathematical Modelling, Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Bonig+H%22">Bonig H</searchLink>; Institute for Transfusion Medicine and Immunohematology, Goethe University, Frankfurt and Red Cross Blood Donation Service Baden-Württemberg-Hessen, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Harter+PN%22">Harter PN</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Reiss+Y%22">Reiss Y</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Hattingen+E%22">Hattingen E</searchLink>; Institute of Neuroradiology, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Rödel+F%22">Rödel F</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Department of Radiotherapy and Oncology, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Plate+KH%22">Plate KH</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; Institute of Neurology (Edinger Institute), Goethe University Hospital, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Tonn+T%22">Tonn T</searchLink>; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden, Dresden, Germany.; German Cancer Consortium (DKTK), Partner Site Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Senft+C%22">Senft C</searchLink>; Department of Neurosurgery, Goethe University Hospital, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Steinbach+JP%22">Steinbach JP</searchLink>; Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.<br /><searchLink fieldCode="AU" term="%22Wels+WS%22">Wels WS</searchLink>; Frankfurt Cancer Institute (FCI), Goethe University, Frankfurt, Germany.; German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt, Germany.; Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany.
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