Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer.
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| Title: | Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer. |
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| Authors: | Tsimberidou AM; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Guenther K; Immatics Biotechnologies GmbH, Tuebingen, Germany., Andersson BS; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Mendrzyk R; Immatics Biotechnologies GmbH, Tuebingen, Germany., Alpert A; Immatics US, Inc., Houston, Texas., Wagner C; Immatics Biotechnologies GmbH, Tuebingen, Germany., Nowak A; Immatics Biotechnologies GmbH, Tuebingen, Germany., Aslan K; Immatics Biotechnologies GmbH, Tuebingen, Germany., Satelli A; Immatics US, Inc., Houston, Texas., Richter F; Immatics Biotechnologies GmbH, Tuebingen, Germany., Kuttruff-Coqui S; Immatics Biotechnologies GmbH, Tuebingen, Germany., Schoor O; Immatics Biotechnologies GmbH, Tuebingen, Germany., Fritsche J; Immatics Biotechnologies GmbH, Tuebingen, Germany., Coughlin Z; Immatics US, Inc., Houston, Texas., Mohamed AS; Immatics US, Inc., Houston, Texas., Sieger K; Immatics US, Inc., Houston, Texas., Norris B; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ort R; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Beck J; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Vo HH; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hoffgaard F; Immatics Biotechnologies GmbH, Tuebingen, Germany., Ruh M; Immatics Biotechnologies GmbH, Tuebingen, Germany., Backert L; Immatics Biotechnologies GmbH, Tuebingen, Germany., Wistuba II; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Fuhrmann D; Immatics Biotechnologies GmbH, Tuebingen, Germany., Ibrahim NK; Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Morris VK; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas., Kee BK; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas., Halperin DM; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas., Nogueras-Gonzalez GM; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kebriaei P; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Shpall EJ; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas., Vining D; Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas., Hwu P; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Singh H; Immatics N.V., Tuebingen, Germany., Reinhardt C; Immatics N.V., Tuebingen, Germany., Britten CM; Immatics N.V., Tuebingen, Germany., Hilf N; Immatics Biotechnologies GmbH, Tuebingen, Germany., Weinschenk T; Immatics N.V., Tuebingen, Germany., Maurer D; Immatics Biotechnologies GmbH, Tuebingen, Germany., Walter S; Immatics US, Inc., Houston, Texas. |
| Source: | Cancer immunology research [Cancer Immunol Res] 2023 Jul 05; Vol. 11 (7), pp. 925-945. |
| Publication Type: | Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101614637 Publication Model: Print Cited Medium: Internet ISSN: 2326-6074 (Electronic) Linking ISSN: 23266066 NLM ISO Abbreviation: Cancer Immunol Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 37172100 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Tsimberidou+AM%22">Tsimberidou AM</searchLink>; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Guenther+K%22">Guenther K</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Andersson+BS%22">Andersson BS</searchLink>; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Mendrzyk+R%22">Mendrzyk R</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Alpert+A%22">Alpert A</searchLink>; Immatics US, Inc., Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Wagner+C%22">Wagner C</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Nowak+A%22">Nowak A</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Aslan+K%22">Aslan K</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Satelli+A%22">Satelli A</searchLink>; Immatics US, Inc., Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Richter+F%22">Richter F</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Kuttruff-Coqui+S%22">Kuttruff-Coqui S</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schoor+O%22">Schoor O</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Fritsche+J%22">Fritsche J</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Coughlin+Z%22">Coughlin Z</searchLink>; Immatics US, Inc., Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Mohamed+AS%22">Mohamed AS</searchLink>; Immatics US, Inc., Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Sieger+K%22">Sieger K</searchLink>; Immatics US, Inc., Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Norris+B%22">Norris B</searchLink>; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Ort+R%22">Ort R</searchLink>; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Beck+J%22">Beck J</searchLink>; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Vo+HH%22">Vo HH</searchLink>; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Hoffgaard+F%22">Hoffgaard F</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ruh+M%22">Ruh M</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Backert+L%22">Backert L</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Wistuba+II%22">Wistuba II</searchLink>; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Fuhrmann+D%22">Fuhrmann D</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Ibrahim+NK%22">Ibrahim NK</searchLink>; Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Morris+VK%22">Morris VK</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas.<br /><searchLink fieldCode="AU" term="%22Kee+BK%22">Kee BK</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas.<br /><searchLink fieldCode="AU" term="%22Halperin+DM%22">Halperin DM</searchLink>; Department of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Texas.<br /><searchLink fieldCode="AU" term="%22Nogueras-Gonzalez+GM%22">Nogueras-Gonzalez GM</searchLink>; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Kebriaei+P%22">Kebriaei P</searchLink>; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Shpall+EJ%22">Shpall EJ</searchLink>; Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Vining+D%22">Vining D</searchLink>; Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Hwu+P%22">Hwu P</searchLink>; Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Singh+H%22">Singh H</searchLink>; Immatics N.V., Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Reinhardt+C%22">Reinhardt C</searchLink>; Immatics N.V., Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Britten+CM%22">Britten CM</searchLink>; Immatics N.V., Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hilf+N%22">Hilf N</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Weinschenk+T%22">Weinschenk T</searchLink>; Immatics N.V., Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Maurer+D%22">Maurer D</searchLink>; Immatics Biotechnologies GmbH, Tuebingen, Germany.<br /><searchLink fieldCode="AU" term="%22Walter+S%22">Walter S</searchLink>; Immatics US, Inc., Houston, Texas. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101614637%22">Cancer immunology research</searchLink> [Cancer Immunol Res] 2023 Jul 05; Vol. 11 (7), pp. 925-945. – Name: TypePub Label: Publication Type Group: TypPub Data: Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101614637 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2326-6074 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223266066%22">23266066 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Immunol Res <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1158/2326-6066.CIR-22-0444 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 925 Titles: – TitleFull: Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Tsimberidou AM – PersonEntity: Name: NameFull: Guenther K – PersonEntity: Name: NameFull: Andersson BS – PersonEntity: Name: NameFull: Mendrzyk R – PersonEntity: Name: NameFull: Alpert A – PersonEntity: Name: NameFull: Wagner C – PersonEntity: Name: NameFull: Nowak A – PersonEntity: Name: NameFull: Aslan K – PersonEntity: Name: NameFull: Satelli A – PersonEntity: Name: NameFull: Richter F – PersonEntity: Name: NameFull: Kuttruff-Coqui S – PersonEntity: Name: NameFull: Schoor O – PersonEntity: Name: NameFull: Fritsche J – PersonEntity: Name: NameFull: Coughlin Z – PersonEntity: Name: NameFull: Mohamed AS – PersonEntity: Name: NameFull: Sieger K – PersonEntity: Name: NameFull: Norris B – PersonEntity: Name: NameFull: Ort R – PersonEntity: Name: NameFull: Beck J – PersonEntity: Name: NameFull: Vo HH – PersonEntity: Name: NameFull: Hoffgaard F – PersonEntity: Name: NameFull: Ruh M – PersonEntity: Name: NameFull: Backert L – PersonEntity: Name: NameFull: Wistuba II – PersonEntity: Name: NameFull: Fuhrmann D – PersonEntity: Name: NameFull: Ibrahim NK – PersonEntity: Name: NameFull: Morris VK – PersonEntity: Name: NameFull: Kee BK – PersonEntity: Name: NameFull: Halperin DM – PersonEntity: Name: NameFull: Nogueras-Gonzalez GM – PersonEntity: Name: NameFull: Kebriaei P – PersonEntity: Name: NameFull: Shpall EJ – PersonEntity: Name: NameFull: Vining D – PersonEntity: Name: NameFull: Hwu P – PersonEntity: Name: NameFull: Singh H – PersonEntity: Name: NameFull: Reinhardt C – PersonEntity: Name: NameFull: Britten CM – PersonEntity: Name: NameFull: Hilf N – PersonEntity: Name: NameFull: Weinschenk T – PersonEntity: Name: NameFull: Maurer D – PersonEntity: Name: NameFull: Walter S IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 07 Text: 2023 Jul 05 Type: published Y: 2023 Identifiers: – Type: issn-electronic Value: 2326-6074 Numbering: – Type: volume Value: 11 – Type: issue Value: 7 Titles: – TitleFull: Cancer immunology research Type: main |
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