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Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.

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Title: Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.
Authors: Chour W; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA., Choi J; Institute for Systems Biology, Seattle, WA, 98109, USA., Xie J; Institute for Systems Biology, Seattle, WA, 98109, USA.; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA, 98195, USA., Chaffee ME; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Schmitt TM; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Finton K; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., DeLucia DC; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Xu AM; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA., Su Y; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA., Chen DG; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Microbiology and Department of Informatics, University of Washington, Seattle, WA, 98195, USA., Zhang R; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA., Yuan D; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA., Hong S; Institute for Systems Biology, Seattle, WA, 98109, USA., Ng AHC; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA., Butler JZ; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Edmark RA; Institute for Systems Biology, Seattle, WA, 98109, USA., Jones LC; Institute for Systems Biology, Seattle, WA, 98109, USA., Murray KM; Institute for Systems Biology, Seattle, WA, 98109, USA., Peng S; PACT Pharma, South San Francisco, CA, 94080, USA., Li G; Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, China.; Key Laboratory of Synthetic Biology Regulatory Element, Chinese Academy of Medical Sciences, Beijing, China., Strong RK; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA., Lee JK; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, 98195, USA., Goldman JD; Swedish Center for Research and Innovation, Swedish Medical Center, Seattle, WA, 98104, USA.; Division of Infectious Disease, Department of Medicine, University of Washington, Seattle, WA, 98195, USA., Greenberg PD; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, 98195, USA.; Department of Immunology, University of Washington, Seattle, WA, 98195, USA., Heath JR; Institute for Systems Biology, Seattle, WA, 98109, USA. Jheath@isbscience.org.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA. Jheath@isbscience.org.
Source: Communications biology [Commun Biol] 2023 May 16; Vol. 6 (1), pp. 528. Date of Electronic Publication: 2023 May 16.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis.
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  Data: <searchLink fieldCode="AU" term="%22Chour+W%22">Chour W</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.<br /><searchLink fieldCode="AU" term="%22Choi+J%22">Choi J</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Xie+J%22">Xie J</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Molecular Engineering & Sciences Institute, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Chaffee+ME%22">Chaffee ME</searchLink>; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Schmitt+TM%22">Schmitt TM</searchLink>; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Finton+K%22">Finton K</searchLink>; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22DeLucia+DC%22">DeLucia DC</searchLink>; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Xu+AM%22">Xu AM</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.<br /><searchLink fieldCode="AU" term="%22Su+Y%22">Su Y</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.<br /><searchLink fieldCode="AU" term="%22Chen+DG%22">Chen DG</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Microbiology and Department of Informatics, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+R%22">Zhang R</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Yuan+D%22">Yuan D</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Hong+S%22">Hong S</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Ng+AHC%22">Ng AHC</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA, 91125, USA.<br /><searchLink fieldCode="AU" term="%22Butler+JZ%22">Butler JZ</searchLink>; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Edmark+RA%22">Edmark RA</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Jones+LC%22">Jones LC</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Murray+KM%22">Murray KM</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Peng+S%22">Peng S</searchLink>; PACT Pharma, South San Francisco, CA, 94080, USA.<br /><searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; Institute of Systems Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, China.; Suzhou Institute of Systems Medicine, Suzhou, 215123, China.; Key Laboratory of Synthetic Biology Regulatory Element, Chinese Academy of Medical Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Strong+RK%22">Strong RK</searchLink>; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.<br /><searchLink fieldCode="AU" term="%22Lee+JK%22">Lee JK</searchLink>; Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Goldman+JD%22">Goldman JD</searchLink>; Swedish Center for Research and Innovation, Swedish Medical Center, Seattle, WA, 98104, USA.; Division of Infectious Disease, Department of Medicine, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Greenberg+PD%22">Greenberg PD</searchLink>; Program in Immunology, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.; Division of Medical Oncology, Department of Medicine, University of Washington, Seattle, WA, 98195, USA.; Department of Immunology, University of Washington, Seattle, WA, 98195, USA.<br /><searchLink fieldCode="AU" term="%22Heath+JR%22">Heath JR</searchLink>; Institute for Systems Biology, Seattle, WA, 98109, USA. Jheath@isbscience.org.; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA. Jheath@isbscience.org.
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  Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2023 May 16; Vol. 6 (1), pp. 528. <i>Date of Electronic Publication: </i>2023 May 16.
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