Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice.
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| Title: | Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice. |
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| Authors: | Bodart-Santos V; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada., Pinheiro LS; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., da Silva-Junior AJ; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Froza RL; Oswaldo Cruz Institute, Oswaldo Cruz Foundation, FIOCRUZ, Rio de Janeiro, Brazil., Ahrens R; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada., Gonçalves RA; Centre for Neuroscience Studies, Department of Biomedical and Molecular Sciences and Department of Psychiatry, Queen's University, Kingston, Canada., Andrade MM; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Chen Y; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada., Alcantara CL; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Grinberg LT; Department of Pathology, University of São Paulo Medical School, Sao Paulo, Brazil.; Memory and Aging Center, Department of Neurology and Pathology, University of California San Francisco, San Francisco, California, USA., Leite REP; Department of Pathology, University of São Paulo Medical School, Sao Paulo, Brazil., Ferreira ST; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Fraser PE; Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., De Felice FG; Institute of Medical Biochemistry Leopoldo de Meis, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Centre for Neuroscience Studies, Department of Biomedical and Molecular Sciences and Department of Psychiatry, Queen's University, Kingston, Canada.; D'OR Institute for Research and Education, Rio de Janeiro, Brazil. |
| Source: | Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2023 Dec; Vol. 19 (12), pp. 5418-5436. Date of Electronic Publication: 2023 May 19. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1552-5279 |
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| DOI: | 10.1002/alz.13134 |
